OverviewThe Research Department at Alnylam is seeking a highly motivated Associate Scientist II to join our innovative Next Wave, Target Discovery and Validation team. Our mission is to discover novel genetically informed targets and experimentally validate them to build a strong foundation for future RNAi-based therapeutics.
This role offers an opportunity to work across a variety of disease areas and build the scientific and experimental biology data package to support the discovery of the next generation of RNAi therapeutics and positively impact patients' lives. The successful candidate will generate high quality in vitro and in vivo data in a collaborative, cross-functional research environment to support a target's nomination from ideation into the drug discovery pipeline. Responsibilities will include developing and executing in vitro cell-based assays, executing studies in in vivo rodent disease models, conducting a variety of molecular biology techniques for transcript and protein quantification, and analyzing, interpreting, and communicating the associated data. A collaborative team mindset, passion and curiosity for science, and a desire to learn new techniques are a must.
This position is
lab based and
on site, located in Cambridge, MA.
Summary of Key Responsibilities- Design, develop, and execute studies to evaluate targets for nomination into RNAi therapeutic discovery programs
- Collaborate closely with other members of cross-functional teams and under the guidance of project leads to ensure project goals are met
- Design, develop, and execute molecular biology assays, in vitro cell-based assays, and in vivo procedures in rodents
- Analyze, document, and interpret experimental data with strong attention to detail and data integrity
- Present and communicate results with key stakeholders within teams and across the organization
Qualifications- Bachelors in a scientific discipline with 1-3 years of relevant laboratory experience or Master degree with 1 year of relevant laboratory experience.
- Industry experience is preferred but not required
- Experience with standard molecular biology techniques is required
- Experience with in vitro cell culture and/or in vivo rodent skills is preferred but not required
- Ability to perform and troubleshoot assays using knowledge of experimental design and underlying scientific principles
- Ability to analyze results, propose future directions, and generate clear reports
- Must be flexible, embrace new tasks and challenges, and able to work on tight deadlines
- Ability to work in a team environment
The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).
Alnylam's robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.
Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers
U.S. Pay Range
$67,600-$101,400 USD
