Job Family:Scientist
Travel Required:None
Clearance Required:Ability to Obtain Public Trust
We are currently searching for a Staff Scientist to provide senior-level bench expertise and scientific leadership, while remaining responsive to related laboratory needs and evolving programmatic priorities within the National Institutes of Health (NIH). This is a full-time, on-site opportunity in Bethesda, MD.
What You Will Do:- Investigate genetic modifiers and biological mechanisms influencing disease severity and clinical outcomes.
- Apply cellular biology, molecular biology, immunology, and bioinformatics methods to study red blood cell dysfunction, acute pain, and inflammation.
- Identify and evaluate biomarkers for monitoring disease processes and treatment response.
- Conduct preclinical studies using animal models, primarily mice, to assess disease mechanisms and investigational therapies.
- Integrate genotype-phenotype analyses with clinical, laboratory, imaging, and diagnostic data to characterize disease manifestations and identify therapeutic targets.
- Evaluate drugs and experimental compounds in preclinical and clinical research to reduce hemoglobin polymerization, improve red blood cell flexibility and flow properties, or increase fetal hemoglobin production.
What You Will Need: - PhD or MD, human genetics, molecular biology, biochemistry, immunology or closely related field.
- Minimum FIVE (5) years of post-doc research experience in areas such as translational research, genetics/ genomics, immunology, and/ or molecular biology.
- Multiple first-author publications in peer reviewed journals.
- Hands-on experience working with murine models, specifically transgenic mice.
- Experience in hematology, vascular biology, red blood cell health, and/or related fields such as nephrology.
- Proficiency in tissue culture, biochemistry and molecular biology assays, gene expression analysis, and/ or processing patient bio-samples.
- Experience with bioinformatics, statistical interpretation, and managing interdisciplinary research projects.
- Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.
What Would Be Nice To Have: - Strong written and verbal communication, organizational, and time management skills.
- Detail oriented.
- Able to work independently as well as collaboratively as a team member.
- Experience in training, teaching, and mentoring junior research staff, graduate students, and post-doctoral fellows is strongly preferred.
- Strong evidence of independent scientific leadership, publications, collaboration management and related skill sets.
The annual salary range for this position is $98,000.00-$163,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.
What We Offer:Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.
Benefits include:
- Medical, Rx, Dental & Vision Insurance
- Personal and Family Sick Time & Company Paid Holidays
- Parental Leave
- 401(k) Retirement Plan
- Group Term Life and Travel Assistance
- Voluntary Life and AD&D Insurance
- Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
- Transit and Parking Commuter Benefits
- Short-Term & Long-Term Disability
- Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
- Employee Referral Program
- Corporate Sponsored Events & Community Outreach
- Care.com annual membership
- Employee Assistance Program
- Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
- Position may be eligible for a discretionary variable incentive bonus
