Staff / Principal Software Engineer

GenBio AI

$250K — $350K *
Healthcare
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 8+ years of industry experience at Staff or Principal level with a focus on production web services and scalable APIs.
  • Mastery of software engineering fundamentals, particularly in clean architecture and modular design.
  • Hands-on experience with integrating large-scale AI and machine learning models into production.
  • Demonstrated ability to design and execute solutions to complex systems problems.
  • Strong cross-functional communication and leadership skills to coordinate between technical teams and scientific product teams.

Responsibilities

  • Lead the development of a software platform for programmable biology, focusing on backend services and APIs.
  • Create clean interfaces connecting frontend applications with backend logic and biological databases.
  • Architect scalable systems for managing complex biological simulations and workflows.
  • Enhance platform performance through optimized design and strategic infrastructure improvements.
  • Collaborate with AI researchers to develop user-facing scientific products that leverage advanced AI capabilities.
  • Coordinate with various teams to create intuitive computational tools for researchers.

Benefits

  • Flexible work environment promoting a healthy work-life balance.
  • Opportunities for professional development and growth within the organization.
  • Access to cutting-edge technology and tools in the field of computational biology.
Full Job Description
We are seeking an experienced Staff to Principal-level Software Engineer to build the user-facing platform that brings these capabilities to computational biologists, experimental scientists, and pharmaceutical researchers. This is a senior individual contributor role for engineers who enjoy solving challenging systems problems while working closely with AI researchers and product teams.

Responsibilities

  • Act as a senior technical leader to build the software platform for programmable biology, developing production-grade backend services and APIs for our Virtual Cell products.
  • Design clean, robust interfaces that seamlessly connect frontend applications, core business logic, massive biological databases, and state-of-the-art AI inference engines.
  • Architect and develop highly scalable systems for complex biological simulations, experiment management, workflow orchestration, and the processing of multimodal biological data.
  • Drive continuous improvements in platform performance and reliability through highly efficient architecture design, strategic caching, asynchronous execution, and optimized distributed infrastructure.
  • Collaborate closely with AI researchers to translate cutting-edge foundation models into reliable, user-facing scientific products that enable virtual perturbations and hypothesis generation.
  • Work cross-functionally across frontend, backend, infrastructure, and machine learning teams to deliver deeply intuitive computational experiences for biologists, experimental scientists, and pharmaceutical researchers.


Qualifications:

  • Extensive industry experience (typically 8+ years) operating at a Staff or Principal level, with a proven track record of building production web services, scalable APIs, and complex distributed backend systems.
  • Exceptional software engineering fundamentals, demonstrating a mastery of clean architecture, modular system design, and the ability to write highly maintainable, performant code.
  • Deep, hands-on experience integrating large-scale AI, LLMs, or machine learning inference systems into highly available production environments.
  • Proven ability to solve challenging, ambiguous systems problems from the ground up, moving from concept to scalable execution.
  • Outstanding cross-functional communication and leadership skills, with the ability to bridge the gap between deeply technical engineering teams, AI researchers, and scientific product teams.


Preferred Qualifications:

  • Domain knowledge or prior experience working with computational biology, genomics, transcriptomics, protein/molecular structures, healthcare, or scientific software.
  • Familiarity with building tools for scientific simulation, automated laboratory experiment management, or complex workflow orchestration.
  • Experience building unified computational frameworks (similar to our AIDO Foundry) that accelerate the development and deployment of AI-native platforms.


$250,000 - $350,000 a year

Join us as we embark on this journey to redefine the future of biology and medicine.

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