Illumina Inc

Sr Mechanical Design Engineer

Illumina Inc$98K — $147K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • 5+ years of relevant experience with a Bachelor's degree, or equivalent experience and education.
  • Bachelor’s or Master’s degree in Mechanical Engineering or a related field.
  • Experience in mechanical design specifically for motorized mechanisms.
  • Proficient in developing electromechanical or mechatronic systems, ideally in instrumentation.
  • Expertise in CAD tools like SolidWorks, Creo, or NX, and familiar with PDM systems.
  • Knowledge of GD&T, DFM/DFA principles, and common manufacturing processes.
  • Hands-on experience in prototyping and testing.

Responsibilities

  • Design and develop custom mechanical mechanisms for genomics instruments.
  • Integrate mechanical designs with electrical, firmware, and control systems.
  • Create and maintain 3D CAD models and engineering documentation.
  • Perform mechanical analyses including tolerance stack-ups and material selection.
  • Build and test prototypes to ensure design effectiveness.
  • Support testing and troubleshooting during development phases.
  • Coordinate with manufacturers on fabrication and assembly.

Benefits

  • Access to genomics sequencing services.
  • Comprehensive family planning options.
  • Health, dental, and vision insurance.
  • Retirement benefits including 401(k).
  • Generous paid time off policy.
Full Job Description

We are seeking a Senior Mechanical Engineer to support new product development in genomics instrumentation. This is a mechanical design focused role working on custom mechanisms and precision motion systems.  Seeking an engineer with experience in designing of motorized mechanisms including a good understanding of control systems.

Responsibilities

  • Design and develop custom mechanical mechanisms for use in genomics instruments, including motion systems, precision assemblies, and fluidic or sample‑handling components.
  • Integrate mechanical designs with electrical, firmware, and control systems
  • Create and maintain 3D CAD models, engineering drawings, and supporting documentation.
  • Perform mechanical analyses such as tolerance stack‑ups, material selection, and basic structural evaluation.
  • Build and evaluate prototypes to verify design intent and system performance.
  • Support system testing, troubleshooting, and iterative refinement during development.
  • Coordinate with suppliers and manufacturing partners on fabrication and assembly processes.

Required Qualifications

  • Typically requires a minimum of 5 years of related experience with a Bachelor’s degree; or 3 years and a Master’s degree; or a PhD without experience; or equivalent work experience.
  • Bachelor’s or Master’s degree in Mechanical Engineering or a related field.
  • Minimum of 5 years of mechanical design experience, mechanisms.
  • Experience developing electromechanical or mechatronic systems, preferably in instrumentation or automation.
  • Proficiency with CAD tools (e.g., SolidWorks, Creo, NX) and familiarity with PDM systems.
  • Working knowledge of GD&T, DFM/DFA principles, and common manufacturing processes.
  • Hands‑on prototyping and testing experience.
  • Ability to manage tasks, communicate clearly, and work effectively with cross‑functional teams.


The estimated base salary range for the Sr Mechanical Design Engineer role based in the United States of America is: $98,400 - $147,600. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off.

About Illumina Inc

Illumina, Inc. is an American company incorporated in April 1998 that develops, manufactures and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression markets. Its headquarters are located in San Diego, California.
Learn more about Illumina Inc
Size
9,800 employees
Market Cap
$30.3 billion
Industry
Net Income
$656 million
Founded
1998
5 Year Trend
+13.5%
Revenue
$3.2 billion
NASDAQ

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