BS/MS Degree in a scientific discipline, ideally life science or chemistry.
Minimum 15 years of experience in pharma or biotech drug discovery and development.
10+ years of Program Management experience, preferably in early-stage development.
Experience in developing advanced therapies for rare genetic diseases is a plus.
Demonstrated leadership of cross-functional teams with strong communication skills.
Passion for innovative medicine and scientific discovery.
Openness to new technologies in drug discovery.
Responsibilities
Lead program teams for AP003 and future programs, fostering scientific rigor and teamwork.
Guide teams in defining scientific questions and translating them into plans and objectives.
Identify and mitigate risks, ensuring critical decisions are assessed for impact.
Develop operational plans with finance to support program activities.
Drive collaboration between functional teams and report on program-related issues to management.
Lead strategic or platform development projects and coordinate business review meetings.
Support the Leadership Team with strategic communications and organizational improvements.
Benefits
Healthcare coverage
Annual incentive program
Retirement benefits
Broad range of additional benefits.
Full Job Description
Sr. Director Program Management & Business Operations
Position Summary:
Alltrna is seeking a talented and highly motivated Sr. Director Program Management and Business Operations, reporting to the President & CFO. The successful candidate is a proven leader with extensive experience in leading research and early drug development program teams from research through the clinic with a particular initial focus on IND enabling and early/mid-stage clinical development. The candidate will be a member of the Company's Leadership Team and will serve as Chief of Staff to the team to drive collaboration, cross-functional clarity, alignment and execution on key priorities and initiatives required to meet the goals of the organization.
Key Responsibilities:
Program Management:
Work closely with the Chief Medical Officer to lead the program team for the Company's lead program, AP003, and future programs instilling a culture of scientific rigor, open debate, collaborative teamwork, sense of urgency and accountability
Possess a comprehensive understanding of the drug discovery process to guide program teams to define the key scientific questions, program strategy and objectives, translating these into optimal deliverables, cross-functional plans, timelines and budgets
Identify bottlenecks, risks, issues and proactively develop appropriate mitigation proposals with input from team members
Ensure all key decisions are identified and properly assessed as to their impact and alternative scenarios developed and evaluated, where appropriate
Work closely with finance and functional teams to develop the operational plans to support program activities with realistic timelines, budget, and resource planning and monitor performance against plans
Interface with and drive collaboration between the various functional teams and with the Leadership Team on program-related matters.
Be the key accountable person for communicating matters related to the programs to management including strategy, work product, updates and issues; producing the one "source of truth" for program-related topics and timelines
Point person for alliance management and coordination, as needed
Lead and/or manage strategic or platform development projects as required and collaborate with Chief Scientific Officer and Research Leadership Team to coordinate relevant content for quarterly business review meetings
Operations:
Collaborate with Leadership Team in development of strategic plans, company goals, long-range planning assumptions, portfolio-level reports and analyses to support business processes and strategic discussions
Develop and deliver impactful presentations that effectively distill complex issues to the critical points and lead to increased understanding and optimized strategic planning & decision-making
Prepare strategic communications utilizing a clear understanding of the business strategy and issues; develop and maintain consistent, relevant content for use in executive-level communications and to further organizational and business goals
Lead the Scientific Communications process, working with the Scientific Communications Committee
Manage schedule, agenda, and content for Leadership Team, Board of Directors and Town Hall meetings
Proactively seek opportunities for organizational improvements (e.g. team structure, processes, communication, etc.)
Other:
Support CEO / LT with partnership discussions and negotiations, including background research, preparation of presentation materials, supporting diligence activities, participating in analysis of terms, etc.
Assist in mapping competitive landscape and proactively identify potential and emerging competitive threats and opportunities
Promote strategic discussions on external trends, competitor strategies, and potential disruptors, and translate these into strategic choices/ recommendations
Collect insights and intelligence from a variety of sources including literature searches, reviewing analyst research, KOL and patient group interactions, etc.
Key Competencies:
This is a highly visible leadership role that requires exceptional interpersonal and communication skills, creative thinking, and early drug development experience that allows one to recognize opportunities/challenges and modify strategy accordingly
The individual will need to have self-confidence and poise to manage complicated programs and projects with multiple stakeholders
The individual will need a sense of urgency and can-do attitude to develop therapies for patients with significant unmet medical needs
Minimum Qualifications:
BS/MS Degree in a scientific discipline, ideally life science or chemistry.
At least 15 years relevant experience in pharma or biotech drug discovery and development, as well as a comprehensive understanding of drug discovery (preclinical and clinical).
10+ years of Program Management experience, preferably in early-stage drug discovery and development.
Experience in the development of advanced therapies to treat rare genetic disease is a plus
Demonstrated experience leading cross-functional teams; strong interpersonal and communication skills
Scientific curiosity and passion for discovering new, innovative medicines.
Openness to embrace new technologies and digital approaches in drug discovery
Proven track record in driving successful, collaborative drug discovery teams.
The salary range for this role is $213,000 - $280,500. Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Alltrna currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Alltrna's good faith estimate as of the date of publication and may be modified in the future.
About Flagship Pioneering
Flagship Pioneering is a life sciences innovation enterprise that conceives, creates, resources, and develops first-in-category life sciences companies. The firm operates through its Flagship Labs unit, which is a dedicated innovation foundry that invents and launches transformative companies. Flagship Pioneering has created over 100 scientific ventures, resulting in over $34 billion in aggregate value, 500+ issued patents, and more than 50 clinical trials for novel therapeutic agents. The firm's portfolio includes companies in the fields of therapeutics, health technologies, and sustainability. Flagship Pioneering was founded in 2000 and is headquartered in Cambridge, Massachusetts.
