Pulse Biosciences, Inc

Sr. Bioengineer, Preclinical Development (In Vivo)

Pulse Biosciences, Inc$135K — $155K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's in Bioengineering or related field with 5+ years of experience or Master's with 3+ years of experience.
  • Strong grasp of anatomy, imaging, and surgical workflows, alongside tissue processing and histology.
  • Experience with energy-based delivery systems preferred.
  • Demonstrated background in preclinical or translational research is required.
  • Familiarity with startup environments preferred.
  • Competence in Microsoft Office Suite applications.
  • Strong analytical, problem-solving, and experimental design skills.
  • Effective communication skills for technical writing and data presentation.
  • Ability to manage multiple priorities in a fast-paced environment.

Responsibilities

  • Lead preclinical study execution, including protocol development and report authorship.
  • Develop and refine both benchtop and in vivo experimental models.
  • Troubleshoot technical challenges related to instrumentation and workflows.
  • Analyze biological and engineering data for product development insights.
  • Support design engineers through testing and parameter optimization.
  • Enhance histology and tissue-processing workflows for data integrity.
  • Mentor junior staff in lab techniques and documentation procedures.
  • Collaborate with teams for regulatory submissions and clinical programs.
  • Prepare technical presentations for internal and external stakeholders.
  • Manage vendor relationships for histology and preclinical services.

Benefits

  • Opportunity to make a significant impact in the healthcare sector.
  • Mentoring opportunities to guide junior staff.
  • Dynamic work environment with varied responsibilities.
  • Involvement in cutting-edge technology and innovations in medicine.
  • Potential for professional growth in a fast-growing company.
Full Job Description
About the Role

The Sr. Bioengineer of Preclinical Development is a key technical contributor responsible for independently executing complex preclinical studies, developing experimental models, and supporting engineering and scientific initiatives that advance the CellFX® nsPFA platform. This role leads portions of preclinical programs, troubleshoots technical challenges, and provides engineering insight that informs device design, treatment algorithms, and clinical strategy. This role mentors junior staff, supports cross-functional teams, and contributes to the generation of high-quality scientific and engineering evidence.

To Make an Impact, You Will:
  • Lead execution of preclinical studies, including protocol development, experimental design input, data collection, and report authorship.
  • Develop and refine benchtop, ex vivo, and in vivo models to support engineering and scientific objectives.
  • Troubleshoot technical issues related to devices, instrumentation, and experimental workflows.
  • Analyze engineering and biological data to generate insights that inform product development.
  • Support design engineers with device testing, verification activities, and treatment parameter optimization.
  • Maintain and improve histology and tissue-processing workflows; ensure data integrity and traceability.
  • Mentor Associate and Engineer-level staff in laboratory techniques, data analysis, and documentation.
  • Collaborate with Clinical, Regulatory, and Engineering teams to support evidence generation for regulatory submissions and clinical programs.
  • Prepare technical presentations and documentation for internal and external stakeholders.
  • Manage vendor relationships related to histology, imaging, and preclinical services.
  • Mentor junior staff and contribute to team development.

To Excel, You Will Bring:
  • Bachelor's Degree with 5+ years of experience or Master's Degree 3+ years of experience in Bioengineering, Biomedical Engineering, Biology, or related field.
  • Strong understanding of anatomy, imaging, surgical workflows, tissue processing, and histology.
  • Experience with energy-based delivery systems is preferred.
  • Experience supporting preclinical or translational research required.
  • Startup experience preferred.
  • Proficient knowledge and skill in Microsoft Office Suite applications.
  • Strong analytical, problem-solving, and experimental design skills.
  • Strong communication skills, including technical writing and data presentation.
  • Ability to independently execute complex preclinical studies.
  • Ability to manage multiple priorities in a dynamic environment.
  • Ability to independently execute complex preclinical studies.
  • Ability to work as a team member, multi-task and be very flexible to adapt to the ever-changing work priorities and requirements of a dynamic, fast growing company.
  • Ability to travel up to 25% of the time, including overnight travel may be required.
  • Ability to lift 25 pounds.

Pay Range:

Compensation is determined based on a wide range of factors including location, job-related skills, experience, education, and training. It is not typical for an individual to be hired at or near the top of the range for their role. This pay range is specific to Northern California location. Base salary range: $135K-$155K. This position is located onsite in Hayward, CA and candidates must reside in the San Francisco Bay Area. No relocation offered.

Ready to Shape the Future of Healthcare?

Apply today to join Pulse Biosciences and help us redefine the boundaries of medicine with bioelectric innovation. To learn more about us, visit our website at www.pulsebiosciences.com.

About Pulse Biosciences, Inc

Pulse Biosciences is a medical technology company developing a proprietary therapeutic tissue treatment platform based on Nano-Pulse Stimulation (NPS), a non-thermal, precise, focal drug-free tissue treatment technology. NPS technology delivers nano-second pulses of electrical energy to non-thermally clear cells while sparing adjacent non-cellular tissue. The Company's CellFX System, powered by NPS technology, is designed to clear unwanted cellular lesions in a broad range of dermatologic conditions. The Company is pursuing a multi-application platform through internal development and collaborations with strategic partners. The Company believes its NPS technology may play a role in immune oncology as a focal tumor treatment as well as in nerve regeneration, and in treating wound healing disorders.
Learn more about Pulse Biosciences, Inc
Size
142 employees
Market Cap
$88.1 million
Industry
Net Income
-$49.8 million
Founded
2014
NASDAQ

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