Twist Bioscience

SOX Compliance Program Manager - Salesforce

Twist Bioscience$110K — $132K *
Information Technology
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 3 to 5 years of experience in program management and compliance support within a regulated environment.
  • Hands-on experience with Salesforce user administration and related change management processes.
  • Active experience with Jira or ServiceNow for ticket management and access controls.
  • Familiarity with SOX compliance concepts and auditor workflows.
  • Bachelor's degree in Information Systems, Business Administration, or related field; Salesforce Certified Administrator preferred.

Responsibilities

  • Assist in audit support by gathering required evidence and documentation for external audits.
  • Process and manage user access and role assignments in alignment with specified SLA metrics.
  • Conduct quarterly and annual user access and role audits to mitigate Segregation of Duties conflicts.
  • Maintain compliance checklists and document system configurations for Salesforce components.
  • Coordinate release schedules and oversee deployment activities across Salesforce environments.
  • Draft and disseminate release notifications to stakeholders; assist with post-deployment testing.
  • Ensure all deployment requests meet documentation and approval standards prior to releases.

Benefits

  • Access to a generous benefits package including health and wellness programs.
  • Eligibility for performance bonuses and equity options.
  • Flexibility with a hybrid work model in South San Francisco.
Full Job Description
Salesforce SOX Compliance & Release Manager (Hybrid in South San Francisco)
Summary

The Salesforce SOX Compliance & Release Manager will maintain and execute our Sarbanes-Oxley (SOX) and Information Technology General Controls (ITGC) frameworks across our enterprise Salesforce environment.

This role will handle day-to-day audit support, access controls, and release coordination, and serve as an operational point of contact for Internal Audit, external auditors (EY), and cross-functional teams to ensure that change management policies and user lifecycle processes are consistently executed and documented.
Core Responsibilities
SOX & ITGC Operational Compliance
  • Audit Support & Evidence Gathering: Assist in pulling walkthrough samples, change tickets, approval logs, and system evidence for external auditors (EY) and Internal Audit.
  • Identity & Access Management (IAM): Process user access, role assignments, and timely deactivations in accordance with SLA metrics via Jira and ServiceNow.
  • Access & Role Reviews: Perform scheduled quarterly and annual user access and profile audits to prevent Segregation of Duties (SoD) conflicts.
  • Checklists & Documentation: Maintain operational compliance checklists, record change logs, and document system configurations for all Salesforce components and custom solutions.
  • Focus on testing, monitoring, and evidencing control effectiveness for regulatory/SOX programs; strong fit for ITGC walkthroughs, sampling, documentation, and audit support.
Release Coordination & Execution
  • Release Logistics: Coordinate release schedules and deployment activities across Salesforce environments and connected integrations.
  • Communication & Verification: Draft release notifications for cross-functional stakeholders and assist with post-production verification testing following system deployments.
  • Ticket & Pipeline Tracking: Ensure all deployment requests in Jira/ServiceNow have appropriate change approvals, business sign-offs, and pre/post-deployment documentation attached before release.
Key Qualifications
  • Experience: 3 to 5 years of experience in program management, compliance support, audit execution and Salesforce administration within a regulated environment.
  • Salesforce Knowledge: Hands-on experience with Salesforce user administration, profiles, permission sets, roles, and basic change management (Sandboxes, deployment steps).
  • Process & Tooling Skills: Active experience using Jira or ServiceNow for ticket management, access controls, and release tracking.
  • Audit Readiness: Familiarity with OTC and ITGC principles, SOX compliance concepts, and auditor evidence-gathering workflows.
  • Education & Certifications:
    • Bachelor's degree in Information Systems, Business Administration, or related field.
    • Preferred: Salesforce Certified Administrator
    • Compliance & Regulatory > Compliance

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.

San Francisco Bay Area Pay Range

$110,000-$132,500 USD

About Twist Bioscience

Twist Bioscience Corporation is a biotechnology company that develops and produces synthetic DNA and RNA. The company's platform allows for the rapid and cost-effective production of custom DNA and RNA sequences, which can be used in a variety of applications such as drug discovery, diagnostics, and data storage. Twist Bioscience's customers include academic and research institutions, pharmaceutical and biotechnology companies, and government agencies. The company was founded in 2013 and is headquartered in San Francisco, California.
Learn more about Twist Bioscience
Size
652 employees
Market Cap
$1.2 billion
Industry
Net Income
-$117.1 million
Founded
2013
5 Year Trend
+80%
Revenue
$101.1 million
NASDAQ

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