Fred Hutch Cancer Center is seeking a Software Development Engineer II to drive the Oncoscape platform, a production-grade system for cancer research.

You will build intuitive user interfaces, design scalable backend systems, and develop analytical methods for high-dimensional data - all while collaborating closely with researchers and clinicians to turn complex scientific questions into robust software and actionable insights. In this role, you will deliver high-impact software and directly contribute to computational oncology research, shaping the platform and the discoveries it enables.

This role involves building and owning full stack features from 0 to 1. The team has an evolving ecosystem including data processing pipelines, one-click deployments into AWS environments for clients, and a growing suite of integrations into various platforms.

 This role will have the opportunity to work partially at our campus and remotely.

• Own and evolve the platform end-to-end: drive design, architecture, and iteration of a production system supporting clinical and genomic research workflows.
• Build high-performance full-stack applications: develop intuitive, scalable interfaces and services using React and TypeScript, enabling exploration of complex, high-dimensional datasets.
• Architect data-intensive systems: design secure, scalable APIs and data models for clinical and genomic data using AWS, balancing performance across client and server layers.
• Bridge research and product: translate ambiguous scientific needs into well-defined product features, analytical tools, and user workflows.
• Shape technical and product direction: contribute to architectural decisions, roadmap prioritization, and overall platform strategy in a dynamic environment.
• Collaborate across disciplines: partner with researchers, clinicians, and engineers to ensure the platform delivers meaningful, actionable insights.

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in computer science or equivalent combination of education and experience.
• Minimum of 3-6 years of directly related experience.
• 3+ years of experience building and shipping full-stack applications from zero to production, using React, TypeScript, and AWS.
• 3+ years designing and delivering scalable, cloud-based systems.
• Proven ability to own and architect end-to-end, data-intensive systems, making sound tradeoffs across frontend, backend, and data processing layers.
• Comfortable operating in ambiguous, fast-moving environments, contributing to both technical architecture and product strategy.
• Experience working in cross-functional teams, translating complex scientific requirements into intuitive, production-grade software.
• Strong analytical abilities and problem-solving skills.
• Knowledge of relational databases and T-SQL.
• Solid understanding of Object-Oriented Programming concepts, data structures and algorithms.
• Understanding of specific programming languages.
• Other department-determined skills or experience may be required.

PREFERRED QUALIFICATIONS:

• Experience with AWS Marketplace and deploying reproducible cloud applications across multiple tenants.
• Demonstrated expertise in high-dimensional data analysis, including dimensionality reduction techniques (e.g., UMAP, PaCMAP, t-SNE) in oncology or genomics contexts. 
• Familiarity with modern genomics workflows and their application to precision oncology and clinical decision-making. 

The annual base salary range for this position is from $99,486 to $157,227, and pay offered will be based on experience and qualifications.

 This role will have the opportunity to work partially at our campus and remotely.Although Fred Hutch is not sponsoring most H-1B visas at this time, candidates who already hold an H-1B sponsored by another organization and are currently in the U.S. may be eligible for this position.Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).