Mass General Brigham

Senior Research Scientist

Mass General Brigham$120K — $145K *
Healthcare
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a biological, chemical, biomedical, or related scientific field required.
  • Significant experience in research leadership, laboratory operations, or research administration in an academic medical center, hospital, or biomedical research environment required.
  • Advanced degree preferred; Master's degree or PhD strongly favored.
  • Demonstrated success overseeing complex research programs, teams, compliance processes, and budgets strongly preferred.
  • Experience working across institutional systems and with multidisciplinary collaborators preferred.

Responsibilities

  • Serve as a senior partner to the Principal Investigator in defining the scientific vision of the Korzenik Lab.
  • Lead laboratory operations ensuring a high-performing research environment.
  • Provide leadership, supervision, and mentorship to research staff and trainees.
  • Oversee research compliance and laboratory safety.
  • Lead budget planning and financial oversight for research activities.
  • Represent the lab in institutional and external partnerships.
  • Enhance operational systems to improve efficiency across the research enterprise.

Benefits

  • Hybrid work environment promoting a balance of in-person and remote activities.
  • Opportunity to work within a high-impact research program dedicated to advancing treatment of primary sclerosing cholangitis.
  • Access to a diverse research portfolio with opportunities for professional growth and collaboration.
  • Supportive culture focused on scientific excellence and operational sustainability.
  • Engaged team culture that fosters inclusion and accountability.
Full Job Description
Site: The Brigham and Women's Hospital, Inc.

Job Summary
The Chief Scientific Officer, Research Strategy and Operations serves as the senior scientific and operational leader for the Korzenik Lab at the Resnek Family Center for Primary Sclerosing Cholangitis Research. Working in close partnership with the Principal Investigator, this role provides high-level leadership across research strategy, program operations, personnel management, regulatory oversight, and institutional collaboration in support of a complex and growing research enterprise.
This individual will play a pivotal role in shaping and executing the Center's scientific and operational vision across basic, translational, and clinical research initiatives. The Executive Lab Director will align people, processes, and resources to advance scientific priorities, strengthen organizational infrastructure, and position the lab for sustained impact, growth, and cross-disciplinary collaboration.
The ideal candidate is an accomplished research leader with a strong scientific foundation, exceptional operational judgment, and the ability to lead through influence in a highly collaborative academic medical environment.

Qualifications

Key Responsibilities

Strategic Scientific and Program Leadership

Serve as a senior partner to the Principal Investigator in defining and advancing the scientific and operational vision of the Korzenik Lab and the Resnek Family Center. Provide leadership across a diverse research portfolio spanning basic, translational, and clinical investigation. Guide the planning, prioritization, and execution of research initiatives to ensure alignment with programmatic goals and institutional standards. Contribute to scientific analysis, interpretation, and the development of presentations, reports, publications, and other scholarly outputs. Anticipate scientific and operational barriers and drive solutions that support research progress and program growth.

Research Operations and Infrastructure

Lead all aspects of laboratory operations, ensuring a high-performing, well-organized, and scalable research environment. Oversee laboratory infrastructure, workflows, scheduling, space allocation, equipment, vendor relationships, and inventory systems. Design and implement operational systems that enhance efficiency, resource stewardship, and execution across the research enterprise. Establish best practices and operating procedures that support consistency, quality, and long-term sustainability.

Leadership, Talent, and Culture

Provide leadership, supervision, and mentorship to research staff, trainees, and laboratory personnel. Build an engaged, inclusive, and accountable team culture grounded in collaboration, professionalism, and scientific excellence. Oversee talent-related processes including onboarding, training compliance, role clarity, and day-to-day staff support. Help develop internal capacity by coaching team members and strengthening operational and research capabilities across the lab.

Regulatory, Compliance, and Risk Oversight

Provide senior oversight for research compliance, laboratory safety, biosafety practices, and regulatory readiness. Direct the preparation, maintenance, and monitoring of relevant research and animal protocols. Serve as the primary liaison to institutional compliance offices, animal care programs, and administrative partners on regulatory and operational matters. Ensure systems are in place to support audit readiness, protocol renewals, and compliance continuity.

Financial and Resource Stewardship

Lead budget planning, expenditure oversight, and financial forecasting for the laboratory and related research activities. Partner with finance, grants, and administrative teams to support sound post-award management and operational decision-making. Monitor resource utilization and identify opportunities for cost containment, vendor optimization, and long-term sustainability. Provide the Principal Investigator with strategic insight into spending trends, operational needs, and resource planning.

Institutional and External Partnership Development

Represent the lab in interactions with institutional leaders, researchers, clinicians, and external collaborators. Strengthen coordination across multidisciplinary teams and support the development of collaborative initiatives and shared resources. Serve as a trusted connector across scientific, operational, and administrative stakeholders to enable effective execution and partnership.

Basic Qualifications

Bachelor's degree in a biological, chemical, biomedical, or related scientific field required. Significant experience in research leadership, laboratory operations, or research administration in an academic medical center, hospital, or biomedical research environment required.

Preferred Qualifications

Advanced degree preferred; Master's degree or PhD strongly favored. Demonstrated success overseeing complex research programs, teams, compliance processes, and budgets strongly preferred. Experience working across institutional systems and with multidisciplinary collaborators preferred.

Leadership Profile

Executive-level judgment and strategic thinking. Strong people leadership and team development capabilities. Operational sophistication and the ability to build high-functioning systems. Excellent communication and relationship management skills. Collaborative leadership style with the ability to influence across functions and levels. Commitment to scientific rigor, operational excellence, and mission-driven research.

Working Environment

This position is based in the Korzenik Lab at the Resnek Family Center for Primary Sclerosing Cholangitis Research and supports a high-impact research program dedicated to advancing understanding and treatment of primary sclerosing cholangitis through integrated basic, translational, and clinical investigation.

Additional Job Details (if applicable)

Remote Type

Hybrid

Work Location

20 Shattuck Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

About Mass General Brigham

Mass General Brigham is an integrated healthcare system that offers patients a continuum of coordinated high-quality care. The system includes primary care and specialty physicians, community hospitals, the two founding academic medical centers, specialty facilities, community health centers, and other health-related entities. Mass General Brigham was founded in 1994 by Brigham and Women's Hospital and Massachusetts General Hospital.

Mass General Brigham Careers

There has never been a more opportune time to join the dedicated team at Mass General Brigham, a leader in healthcare innovation and community health services. This esteemed company is actively seeking to expand its professional family with individuals passionate about making a significant impact in the medical field.

Explore Job Opportunities

Mass General Brigham offers a variety of job opportunities that cater to a range of skills and experiences. Whether it's through patient care, research, or administrative roles, each position contributes to the overarching mission of improving health outcomes across diverse communities.

Engage in Professional Growth

Mass General Brigham is committed to the professional growth and continuous education of its team members. With robust leadership programs and diversity training, employees are equipped to ascend in their careers while fostering an inclusive environment.

Experience the Culture of Innovation

At Mass General Brigham, innovation is at the core of the company culture. The team is encouraged to lead in the development of cutting-edge medical treatments and solutions that set new standards in healthcare.

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For those starting their career, Mass General Brigham offers internships that provide invaluable industry experience and a chance to develop essential skills in a real-world setting. These internships often lead to full-time employment, thanks to the company's emphasis on hiring interns who exhibit a strong work ethic and a drive for continuous learning.

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Employees at Mass General Brigham enjoy a comprehensive package of benefits designed to support both their professional and personal lives. From health and wellness programs to family care support, the company ensures that team members have the resources they need to thrive both at work and at home.

Join a Team Committed to Excellence

Mass General Brigham is not just hiring; it's building a future. The company looks for curious, creative, and solution-driven team players ready to contribute to a culture of care and excellence.

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