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Job Summary
Job ID 276341
The Georgia Cancer Center (GCC) at Augusta University (AU) is actively seeking a highly motivated faculty member at the rank of Senior Research Scientist, with a deep immunology background to join our booming research team driving CAR-T Cell Therapy discovery research. The faculty member will play a crucial role in the design, development, optimization, and nomination of CAR-T cell candidates using various in vitro and in vivo phenotypic and functional assays, and will work closely with our cross-functional teams to advance our exciting lead CAR-T candidates to clinical application. This position is not considered to be on tenure track.
Responsibilities
Research - 50%
- Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products.
- Genome editing and culturing human pluripotent stem cells in various conditions.
- Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection.
- Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization.
Reporting Research - 50%
- Support engineered T cell production activities (e.x. gene editing, T cell culture, cryopreservation, cell thawing).
- Culture both engineered primary T cell and suspension/adherent cell lines.
- Support IND-enabling preclinical studies.
- Coordinate tasks across multiple projects and teams, demonstrating prioritization and planning.
Required Qualifications
-PhD or equivalent in Cell or Molecular Biology/Biological Sciences with 10 or more years research experience.
-Extensive hands-on experience with Molecular Biology (as PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), Cloning, mammalian cell culture and transfection.
-Experience with multi-color flow cytometry, panel design, and data analysis.
-Willingness to accept responsibilities outside of initial job description
Preferred Qualifications
- Experience with human CAR T cell engineering.
- Experience using viral (lentiviral, retroviral or AAV) and/or non-viral gene delivery methods (e.g., CRISPR mediated knock-in or targeted genome integration).
- Experience with immunological assays, such as cytokine/chemokine analysis (e.x. ELISA or Luminex), cytotoxicity and in vitro cell based assays live cell analysis.
- Proficiency in using data analysis tools such as FlowJo and GraphPad Prism.
- Understanding of US FDA cGMP and international regulatory requirements is welcomed.
Shift/Salary/Benefits
This position is fiscal year based and works year-round.
The intended work commitment or full-time equivalent (FTE) for this position is 1.0 and considered full-time.
Salary and compensation is commensurate with education, experience, and achievements. The salary is subject to availability of funds.
Comprehensive benefits include medical, dental, vision, 13 paid holidays, vacation leave, sick leave, generous retirement plans, tuition waiver, wellness options, and much more!
Also, our full-time employees who have been employed with us successfully for more than 6 months can be considered for the Tuition Assistance Program.
Rank and salary are determined at the time of hire and are based on a variety of factors including but not limited to experience, education, credentials, specialty, training, etc. while also considering internal equity and market data.
Advancement through the faculty ranks at Augusta University is only through the annual Promotion and Tenure process in which faculty may apply if eligible (typically five-year increments). For more information on ranks, please review the Augusta University Promotion and Tenure Website:
https://www.augusta.edu/faculty-affairs/promotionandtenure.php
College/Department Information
The Medical College of Georgia is one of the nation's largest medical schools by class size, with 260 students per class. The educational experience is anchored by the main campus in Augusta, regional clinical campuses for third- and fourth-year students across the state and a second four-year campus in Athens in partnership with the University of Georgia. MCG's expanding partnerships with physicians and hospitals across Georgia currently provides about 350 sites where students can experience the full spectrum of medicine, from complex care hospitals to small-town solo practices. MCG and its teaching hospitals also provide postgraduate education to more than 500 residents and fellows in 50 different Accreditation Council for Graduate Medical Education-approved programs. Our researchers and clinicians focus on what most impacts the health of Georgia's and America's children and adults, including cardiovascular biology and disease, cancer, neurosciences and behavioral sciences, public and preventive health, regenerative and reparative medicine, personalized medicine and genomics. Our physician faculty also share their expertise with physicians and patients at about 100 clinics and hospitals statewide.
Location
Our Health Sciences Campus:
1120 15th Street, Augusta, GA 30912
Conditions of Employment
All selected candidates are required to successfully pass a Background Check review prior to starting with Augusta University.
If applicable for the specific position based on the duties: the candidate will also need to have a credit check completed for Positions of Trust and or approved departmental Purchase Card usage.
Motor vehicle reports are required for positions that are required to drive an Augusta University vehicle.
For Faculty Hires: Final candidates will be required to provide proof of completed academic degree(s) as well as post-secondary coursework in the form of original transcript(s). Those candidates trained by a foreign institution will also be required to provide an educational/credential evaluation.
All employees are responsible for ensuring the confidentiality, availability, and integrity of sensitive [patient, student, employee, financial, business, etc.] information by exercising sound judgment and adhering to cybersecurity and privacy policies during their employment and beyond.
How To Apply
To be considered an applicant for this position, you must apply online at https://www.augusta.edu/hr/jobs/#job-portals .
Please upload your Curriculum Vitae, Research Statement, Professional References, etc., as one document.
Other Information
This position is also responsible for promoting a customer-friendly environment and providing superior service to our patients, students, faculty, and employees. "Augusta University is a patient-and family-centered care institution, where employees partner every day with patients and families for success."
Augusta University is a tobacco-free environment, and the use of any tobacco products on any part of the campus, both inside and outside, is strictly prohibited.
