The RoleThe Senior Research Associate, Platform RNA Sciences, will work on key projects to advance Sail's first-in-class programmable circular RNA technology (Endless RNA™ or eRNA). This role will help optimize eRNA purification processes, improve circularization, and upgrade our eRNA design. The successful candidate is organized, and attentive to details, a fast learner with a strong sense of responsibility who takes pride in his/her work. The team looks forward to helping you strive in this exciting and fast-paced environment to make a real-world impact on patients' lives.
Responsibilities - Perform experiments to optimize eRNA purification
- Determine circularization efficiency and impurity levels by running analytic assays
- Conduct library and small scale eRNA production for platform learning projects
- Monitor RNA immune reactivity and protein expression in cells
- Design properly controlled experiments, generate high-quality data, and run rigorous statistical analysis
- Maintain detailed documentation in electronic lab notebooks
- Present findings clearly to platform teams and contribute to scientific discussions and decision-making
Qualifications- B.S. in Life Sciences, Chemistry, Engineering, or a related field with 4+ years or M.S. with 2+ years of full-time industry or academic research experience
- Experience using data analysis and information management tools, such as Excel, Graphic Prism, JMP, SnapGene, Benchling
- Ability to manage multiple tasks at once while knowing how to prioritize
- Strong collaborative spirit and communication skills
- Excellent record keeping
Preferred Qualifications- Experience in RNA production and purification
- Familiarity with high-performance liquid chromatography (HPLC) or other column-based purification/analytic methods
- Experience in cell culture and assays to monitor protein expression (e.g., ELLA, ELISA, IncuCyte, flow cytometry)
Salary Range: $75,000 - $95,000
