Sr Director Therapeutic Area (Hepatology)- US- Remote
Senior Director, Drug Development & Consulting 6 Cardiometabolic
At ICON plc, we are driven by commitment to People, Clients, and Performance. We are seeking a strategic Cardiometabolic expert to join our Drug Development & Consulting team in a highly visible, client-facing role.
This position offers the opportunity to act as a trusted advisor to senior stakeholders across the industry, including CEOs, CMOs, and other Cardiometabolic Therapeutic Area Heads. You will deliver bespoke, asset-centric solutions while shaping Cardiometabolic drug development strategies across the full lifecycle.
The Role
This is a consultative and advisory role where you will serve as a key scientific partner to both external clients and internal teams. Often acting as the first technical point of contact, you will play a critical role in pre-sales activities, proposal strategy, and long-term partnership development within Cardiometabolic.
Key Responsibilities
- Lead strategic Cardiometabolic drug development design, delivering tailored, asset-focused solutions across liver diseases including MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, viral hepatitis, and other chronic and rare liver conditions like PBC, PSC, PFIC
- Own end-to-end protocol development, including design, scientific review, and evaluation for Cardiometabolic clinical trials across Phases I 6IV
- Partner directly with senior client stakeholders (e.g., CMO, TA Heads, Clinical Development leadership) to provide expert guidance on Cardiometabolic development strategy and data interpretation
- Act as scientific and strategic lead in proposal development, study strategy, and bid defense activities within Cardiometabolic
- Build and maintain strong relationships with Cardiometabolic key opinion leaders (KOLs), advisory boards, and relevant regulatory authorities
- Contribute to the development of Cardiometabolic-focused service offerings, supporting innovation and growth in liver disease drug development capabilities
- Provide training, mentorship, and thought leadership in Cardiometabolic to internal teams and external partners
- Participate in portfolio reviews, governance discussions, and scientific oversight of Cardiometabolic programs
- Support operational teams with high-level scientific input, including investigator meetings and Cardiometabolic-specific study discussions
- Represent the organization at Cardiometabolic congresses and scientific forums to promote clinical excellence and scientific leadership
What You Bring
- Deep, recognized expertise in Cardiometabolic and liver disease drug development
- Strong understanding of Cardiometabolic clinical trial design, biomarkers, endpoints (e.g., fibrosis staging, histologic and non-invasive markers), and evolving therapeutic landscapes (e.g., MASLD/MASH, alcohol-associated liver disease (ALD), cirrhosis, immuno-Cardiometabolic approaches and antiviral therapies)
- Proven ability to operate in a strategic, client-facing, consultative environment within pharmaceutical or clinical research settings
- Experience engaging and influencing senior scientific and clinical stakeholders across industry and academia
- Excellent communication and presentation skills, with the ability to translate complex Cardiometabolic data into clear, actionable development insights
- Collaborative, global mindset with strong cross-functional leadership capability
- MD required, ideally with specialization or substantial clinical/research experience in Cardiometabolic diseases
Additional Information
- 20- 40% travel (domestic and international)
- Opportunity to work in a highly visible, impact-driven role shaping the future of Cardiometabolic drug development
**Actual compensation will be determined based on the candidate 27s relevant experience, skills, education and training, geographic location, and other job-related factors.
#LI-MN1
#LI-Remote
Rewards & Benefits
ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.
Benefits may include:
- Competitive base salary and performance related incentives
- Health and wellbeing programmes including medical, dental, and vision coverage where applicable
- Retirement and pension plans
- Life assurance and disability coverage
- Employee assistance programmes and wellbeing resources
- Learning and development opportunities through structured training and career pathways
Benefits may vary depending on role and location.
Visit our to read more about the benefits ICON offers.
Salary Range
$195,808.00-$244,760.00
Are you a current ICON Employee? Please click to apply
