Semantic / Ontology Lead

Biorce

$110K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Advanced degree (MS/PhD) in biomedical informatics, computer science, or related field, or equivalent experience.
  • Experience building or maintaining ontologies/taxonomies in healthcare or life sciences.
  • Strong knowledge of clinical vocabularies (SNOMED CT, LOINC) and data standards (CDISC, HL7 FHIR).
  • Hands-on experience with ontology/knowledge-graph tools (OWL, SPARQL, Protégé).
  • Excellent written and verbal communication skills in English.

Responsibilities

  • Design and maintain ontologies and taxonomies for clinical concepts using established standards.
  • Ensure interoperability across clinical data standards like CDISC and HL7 FHIR.
  • Collaborate with Data Architecture to integrate semantic structures into the platform.
  • Partner with AI/ML teams to provide structured knowledge representations.
  • Map external data sources to semantic layers for new integrations.
  • Document and govern the evolution of the ontology over time.

Benefits

  • Dynamic work environment with a diverse international team.
  • Work alongside top talent committed to impactful work.
  • Receive a MacBook to enhance productivity.
  • Comprehensive benefits package for you and your family.
  • Health insurance (medical, dental, vision) effective shortly after start date.
  • Hybrid work model for better work-life balance.
  • Company events for celebrating achievements.
  • Pet-friendly office environment.
Full Job Description
About the role

Following our successful expansion into the U.S. and continued growth across Europe, we are seeking a Semantic/Ontology Lead to help drive our Data function from our Austin hub. This person will play a critical role in owning how Aika represents and connects clinical and scientific knowledge.

Rather than treating clinical data as isolated fields and tables, this person builds the semantic backbone that lets Aika reason consistently across terminologies, standards, and data structures - turning fragmented, messy clinical data into something the platform can genuinely understand and connect.

Who We're Looking For:

Someone with real experience building or maintaining ontologies and taxonomies in a healthcare or life sciences context. This person should be able to translate semantic design into something data engineers and AI teams can actually build against.

Key Responsibilities:

  • Design and maintain ontologies, taxonomies, and controlled vocabularies for clinical and scientific concepts, grounded in established standards (SNOMED CT, MedDRA, LOINC, RxNorm)
  • Ensure semantic interoperability across clinical data standards (CDISC SDTM/ADaM, HL7 FHIR, OMOP CDM)
  • Partner with Data Architecture and Engineering to embed semantic structure directly into the platform - schemas, knowledge graphs, metadata layers
  • Work with AI/ML teams to ensure models have access to structured, well-defined knowledge representations
  • Map and align external data sources and terminologies to Biorce's semantic layer as new integrations come online
  • Own documentation and governance for how the ontology evolves over time


Requirements

Must-haves

  • Advanced degree (MS/PhD) in biomedical informatics, computer science, linguistics, or a related field - or equivalent hands-on experience
  • Real experience building or maintaining ontologies/taxonomies in a healthcare, life sciences, or clinical research context
  • Strong working knowledge of clinical/biomedical vocabularies (SNOMED CT, MedDRA, LOINC, RxNorm) and clinical data standards (CDISC, HL7 FHIR, OMOP)
  • Hands-on experience with ontology/knowledge-graph tooling (OWL, RDF, SPARQL, Protégé, or equivalent)
  • Excellent written and verbal communication skills in English


Nice-to-Haves

  • Experience supporting large-scale enterprise data integration efforts
  • Familiarity with how structured knowledge/knowledge graphs improve LLM grounding and reasoning
  • Background in regulatory-facing clinical data (FDA/EMA submissions)


Why Join Us?

  • A dynamic work environment with an international team, where collaboration and diversity thrive.
  • Work alongside top talent, united by a shared purpose and committed to making a real impact.
  • Get equipped with a MacBook to enhance your productivity and work experience.
  • Benefits package designed to support you and your family's overall well-being.
  • Comprehensive medical, dental, and vision insurance options, effective from your start date or shortly thereafter depending on location.
  • Hybrid work model offering flexibility to balance your professional and personal life.
  • Company events to celebrate achievements and enjoy time together.
  • Our office is pet-friendly! You'll likely be greeted by a few wagging tails upon arrival.


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