Scientist, Stem Cell Biology

Conception

$95K — $115K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD or equivalent experience in stem cell biology or related field.
  • Strong hands-on experience with human and/or nonhuman primate iPSCs or ESCs.
  • Proven ability in PSC derivation, culture, differentiation, and characterization.
  • Demonstrated skill in independently designing and executing experiments.
  • Experience with transcriptomic and epigenetic data analysis, including single-cell datasets.
  • Exceptional experimental judgment and attention to detail.

Responsibilities

  • Build and advance pluripotent stem cell systems for reproductive cell development.
  • Develop and optimize PSC derivation and differentiation approaches.
  • Design experiments to drive differentiation success and assess cell quality.
  • Implement molecular and epigenetic readouts to characterize cell identity.
  • Leverage experimental and computational data for troubleshooting and progress assessment.

Benefits

  • Competitive pay and company equity.
  • Excellent healthcare benefits.
  • Collaborative research environment focused on impactful results.
  • Strong funding and connections in Silicon Valley.
Full Job Description
Experience level: PhD or equivalent industry experience. Demonstrated independent ownership of complex stem cell workflows and experimental programs.

For this role, we are looking for someone with deep expertise in pluripotent stem cells.

The position

We are looking for an excellent, hands-on stem cell scientist with demonstrated experience working with pluripotent stem cells and independently driving complex experimental work.

Strong stem cell experience is critical. We are particularly interested in scientists who have worked extensively with human and/or nonhuman primate iPSCs or ESCs, including stem cell derivation or line establishment, expansion, banking, differentiation, and characterization.

At the Scientist level, we expect someone to independently own technically complex workflows: design experiments, execute them carefully, troubleshoot when they fail, interpret the resulting data, and determine what to do next. You should be comfortable systematically improving protocols rather than simply following them.

Experience taking PSCs through differentiation into specialized cell states is particularly valuable. Experience with QC assay development, epigenetic characterization, 3D culture, reproductive or developmental biology, and computational analysis of genomic readouts is also highly relevant.

This is a bench-heavy role. We are looking for someone who likes doing difficult experimental work and is comfortable executing, troubleshooting, repeating, improving, and mastering technically demanding workflows.

What you'll do
  • Build and advance pluripotent stem cell systems that are central to developing stem-cell-derived reproductive cells
  • Develop and optimize approaches for PSC derivation, differentiation, and cell-state control
  • Design experiments to understand what drives successful differentiation, cell quality, and developmental progression
  • Build molecular and epigenetic readouts to characterize cell identity, quality, and function
  • Use experimental and computational data to uncover what is working, what is failing, and what to try next


What we're looking for
  • PhD or equivalent experience in stem cell biology, developmental biology, reproductive biology, cell biology, bioengineering, or a related field
  • Strong hands-on pluripotent stem cell experience is required, ideally with human and/or nonhuman primate iPSCs or ESCs
  • Experience with PSC derivation or line establishment, culture, differentiation, and characterization
  • Demonstrated ability to independently design, execute, troubleshoot, and interpret experiments
  • Experience analyzing and interpreting transcriptomic and epigenetic sequencing data is highly desirable, including bulk and/or single-cell datasets
  • Excellent experimental judgment, attention to detail


We are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, excellent healthcare benefits, and a collaborative research environment focused on meaningful results.

If you are passionate, hardworking, and aligned with our mission, we want to hear from you.

To learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104

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