Location: San Diego, CA
Job Type: Full-Time
Compensation: $90,000 to $120,000
Position OverviewWe are seeking a Scientist I/II, Enzyme Assay & Characterization to play a key role in developing and executing biochemical assays that support the company's multi-omics platform development. This individual will optimize and implement assays.
The Scientist I/II will contribute directly to enzyme evaluation. This role offers opportunities for broad technical growth, including assay development, molecular biology, protein engineering and integration.
The candidate must be detail-oriented, analytical, and collaborative, thriving in a dynamic environment that values innovation, cross-disciplinary interaction, and scientific rigor.
Key Responsibilities- Clone, express, and screen protein constructs in bacterial expression systems.
- Optimize bacterial expression conditions.
- Execute purification workflows.
- Characterize protein quality.
- Optimize and implement biochemical assays.
- Develop, optimize, and validate spectroscopic and fluorescence-based assays.
- Troubleshoot and refine assays for reproducibility, sensitivity, and throughput.
- Collaborate closely with protein expression/purification, enzymology, protein engineering, and molecular biology teams.
- Document methods, maintain rigorous records, contribute to SOPs and prepare data summaries and reports.
- Support lab organization, maintain equipment, and ensure compliance with safety and reproducibility practices.
Qualifications- B.S. in Biochemistry, Molecular Biology, Enzymology, or related field with 2-6 years of relevant experience, OR M.S. with 0-4 years of relevant experience. Level of position will depend on educational credential and years of experience.
- Demonstrated experience optimizing and implementing biochemical assays.
- Hands-on experience with spectroscopic and fluorescence-based assays.
- Hands-on experience with gel electrophoresis and gel-based assays.
- Strong experience with data visualization software.
- Excellent organizational, problem-solving, and communication skills.
- Ability to work independently and collaboratively in cross-functional teams.
