We are seeking a highly skilled and motivated Scientist to join our Antibody Discovery Group. The successful candidate will play a critical role in advancing our antibody discovery efforts through various techniques, including immunogen design, B-cell sorting, flow cytometry, ELISA, and yeast library screening. This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.
Responsibilities - Design and execute antibody discovery campaigns from immunization to lead delivery.
- Perform high throughput sorting to isolate specific B cell populations.
- Design, execute, and analyze FACS experiments to validate and characterize antibodies.
- Develop, optimize, and perform assays (ELISA, BLI, flow cytometry) for antibody screening and specificity testing.
- Conduct yeast display library screening to identify and analyze antibody candidates.
- Analyze experimental data and prepare detailed reports and presentations.
- Work with cross-functional teams and contribute to project planning and strategy.
- Maintain accurate records, ensure safety compliance, and contribute to lab organization.
Qualifications- Ph.D. in Immunology, Molecular Biology, Biochemistry, or a related field with 0-2 years of industry experience.
- 3-7 years of hands-on experience in B-cell sorting and screening through flow cytometry, ELISA and bio-layer interferometry.
- Proficiency in flow cytometry and cell sorting techniques.
- Experience in biolayer interferometry (affinity, avidity, binning) or similar assays.
- Strong background in ELISA assay development and optimization.
- A proven track record of working with Sony cell sorters or similar instruments is preferred.
- Experience with single-cell analysis platforms (i.e., Beacon) is highly desirable.
- Experience in antibody discovery and development is highly desirable.
- Experience in NGS library preparation and BCR repertoire analysis is a plus.
- Expertise in molecular biology techniques related to yeast display libraries, including preparation, culture and screening is preferred.
Compensation and Benefits:
The expected base salary range for this position is $90,000 - $115,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate's level qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.
SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.
We offer an opportunity for you to learn and grow while making significant contributions to the company's success.
