Description:
Job Overview
The candidate will be assisting in deep analytical characterization of cell therapy product. You will also be assisting in planning and executing laboratory studies, analyze experimental data and carefully document resultant information. You will participate in laboratory activities to support analytical and process development as well as the characterization of Kite's T cell products.
Responsibilities (include but are not limited to):
• Execute flow cytometric testing on a regular basis or as needed, in support of process development and product characterization
• Perform data analysis, data reporting, and further statistical analysis with advanced analysis software
• Assist in data verification to ensure data integrity
• Maintain, calibrate and operate flow cytometry analytical equipment and Client cell sorter
• Implement reagent titration, lot-checking, and maintain proficiency testing database
• Transfer flow cytometry assays from the method development group to analytical testing group
• Develop templates for standard operating procedures and analytical test methods
• Write, review and edit accurate technical documents
• Assist in developing, qualifying, executing and documenting &Client;10 color flow cytometry methods to study and characterize processes for production of T cell therapies
• Provide user training on instruments, sample analysis, and cross-train analysts on analytical methods
• Coordinates activities for members of project teams in the initiation and execution of laboratory experimentation
• Participate in sampling and study plan meetings to support different functional areas within Process Development
• Additional responsibilities may be assigned to reflect changes in business processes.
Qualifications
• BSc or MSc degree with 3 plus years experience in cell therapy areas.
• Demonstrated strong knowledge of developing flow cytometry methods, and technical knowledge of instrument, method controls
• Proficient in operating CytoFLEX S/LX, Client FACSCanto, Client FACSAria II and CliniMACS
• Excellent skill in Microsoft word, Excel, MS Teams, Prism, Diva, CytEXPERT, and FlowJo data analysis software
• Understand deep characterization knowledge in patient materials, product knowledge, and process characterization
• Demonstrates emerging ability in developing methods, techniques and evaluation criteria for obtaining results and interpreting experimental outcomes
• Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench
• Ability to think critically, demonstrate troubleshooting and problem solving skills
• Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment
• Previous experience with other technologies is a plus
• Highly collaborative with excellent interpersonal, verbal and written communication skills
• Comfortable working in a fast-paced company environment with minimal direction and able to adjust workload/assignments based upon changing priorities
• Self-motivated, detail-oriented, and willing to accept temporary responsibilities outside of initial job description
