Hands-on mastery of advanced flow cytometry techniques.
Expertise in analyzing low-input biological samples.
Strong foundational knowledge of immunology and tumor biology.
Proficient in sterile cell culture techniques.
Detail-oriented team player with strong communication skills.
Experience or willingness to develop in-vivo models.
Responsibilities
Generate robust data to advance oncology targets into clinical development.
Design and execute complex flow cytometry experiments as the technical expert.
Build and optimize high-parameter multicolor flow cytometry panels.
Analyze challenging low cell count samples with meticulous attention.
Collaborate with project teams to present complex data insights.
Maintain and manipulate primary human/murine cells and established cell lines.
Execute in vitro assays using rigorous cell culture techniques.
Benefits
Comprehensive health insurance options.
Retirement savings plan with company match.
Generous paid time off and holidays.
Professional development opportunities.
Collaborative and innovative work environment.
Full Job Description
The Opportunity
Join our Translational Oncology department as a Scientist 3, where your technical precision and deep immunological expertise will bridge the gap between early discovery and life-changing clinical therapies. In this pivotal, lab-based role, you will serve as our go-to flow cytometry expert, thriving in a collaborative, fast-paced environment that empowers bold scientific inquiry.
Advance Oncology Pipelines: Generate robust, reproducible data to propel novel oncology targets from exploratory discovery straight into clinical development.
Lead Flow Cytometry Execution: Design, execute, and analyze highly complex flow cytometry experiments, acting as the primary technical subject matter expert for the team.
Innovate Multicolor Panels: Build, optimize, and troubleshoot large, high-parameter multicolor flow cytometry panels to enable deep immunophenotyping.
Master Low-Input Samples: Perform rigorous, meticulous analysis on challenging, scarce samples, specializing in low cell count workflows.
Drive Cross-Functional Strategy: Partner seamlessly with diverse project teams, translating and presenting complex data insights to influence key strategic decisions.
Execute In Vitro Assays: Maintain and manipulate both primary human/murine cells and established cell lines using rigorous cell culture techniques.
Who you are
You hold a PhD in Immunology, Oncology, or a closely related scientific discipline.
You bring exceptional, hands-on mastery of advanced flow cytometry, with a proven track record of building and troubleshooting large multicolor panels.
You possess demonstrated expertise in analyzing challenging, low-input/low cell count biological samples.
You have a deep, foundational understanding of immunology and tumor biology.
You are proficient in sterile cell culture techniques involving both primary cells and established cell lines.
You are an adaptable, detail-oriented team player with strong communication skills who thrives when navigating shifting priorities.
You have experience or are willing to develop in-vivo models.
Documented record of professional achievement in the form of high-quality publications.
Preferred
Postdoctoral research experience in an academic or industry setting.
Prior hands-on experience working in cell therapy (e.g., CAR-T, TCR-T, or NK cell therapies).
Location
This is a lab-based role at our South San Francisco, CA campus. Onsite presence is required.
Relocation benefits are not available for this job posting.
The expected salary range for this position based on the primary location of South San Francisco, CA is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
About Roche
Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
