Research Scientist - Nucleic Acids Chemistry R&D

Centrillion Biosciences, Inc.

$90K — $130K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in organic chemistry with lab experience in synthesis and bioorganic chemistry.
  • Hands-on experience in nucleoside, nucleotide, and oligonucleotide synthesis.
  • Expertise in preparing conjugates with fluorescent dyes.
  • Proficient in instrumental analysis techniques: NMR, HPLC, MS, FTIR.
  • Knowledge of polymer and surface chemistry is a plus.
  • Proven track record in executing independent and joint research projects.
  • Strong communication skills with a history of scientific publications.

Responsibilities

  • Plan and conduct research experiments in nucleic acid technology.
  • Synthesize, modify, and characterize nucleotides and oligonucleotides.
  • Prepare fluorescent dye conjugates for nucleotides.
  • Modify and characterize materials for solid-phase synthesis.
  • Collaborate with scientists and engineers on projects.
  • Document experimental findings and present results.
  • Prepare SOPs and written methods for laboratory work.
  • Maintain laboratory and analytical equipment.

Benefits

  • Collaborative work environment in a multidisciplinary research team.
  • Opportunity to advance research in nucleic acid analysis technologies.
  • Hands-on experience with cutting-edge scientific techniques.
  • Potential for professional development and skill enhancement.
Full Job Description
Job Description

Centrillion Biosciences is seeking a creative, energetic, resourceful organic chemist to join a multidisciplinary research team developing new technologies for nucleic acid sequence analysis.

Duties:
  • Plan and execute applied research experiments involving:
  • Synthesis, modification and characterization of modified nucleotides, nucleoside polyphosphates and oligonucleotides
  • Preparation of fluorescent dye conjugates of nucleotides and oligonucleotides.
  • Materials modification and characterization for solid phase synthesis
  • Collaborate with and/or supervise other scientists & engineers on joint projects.
  • Documentation of experimental work; analysis of data; documenting and presenting results
  • Preparation of written methods and SOPs
  • Operation and maintenance of laboratory & analytical equipment
  • Support R&D and Pilot Manufacturing Operations and QC


Qualifications
  • PhD in organic chemistry, with extensive training and practical laboratory experience in organic synthesis, physical organic and bioorganic chemistry.
  • Experience with nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
  • Experience preparing fluorescent dye conjugates of nucleotides and oligonucleotides.
  • Proficiency in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
  • Working knowledge and practical experience with polymer and surface chemistry is strongly desired.
  • Demonstrated ability to plan and execute independent and collaborative research projects.
  • Demonstration of goal-oriented, hands-on and innovative approach to problem solving.
  • Excellent written and oral communication skills.
  • Co-authorship on one or more publications in peer-reviewed scientific journals.
  • She/he will be required to develop additional competencies, and apply practical skills and knowledge to solving a variety of applied scientific and technical problems.


Additional Information

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