Job Description
Field of research:
Single particle cryo-electron microscopy and X-ray crystallization of viral glycoproteins, immunogen design, virology, biochemistry and biophysics.
Purpose of the Research Project(s):
The goal of our research is to develop vaccines and therapeutics targeting human pathogens.
Duties and Responsibilities:
20% Structure-based and machine-learning immunogen design for protein subunit and mRNA vaccines based on viral surface glycoproteins (construct design, recombinant expression in mammalian cells, purification, and stability assays),
20% Characterize protein antigenicity (binding assays using ELISAs, SPR and biolayer interferometry to evaluate binding kinetics and affinity of antibodies or designed proteins),
15% Perform structural studies (high-throughput cryo-electron microscopy of subunit vaccines as well as of complexes between viral glycoproteins and monoclonal and polyclonal antibodies as well as X-ray crystallography),
10% Design and execution of virology assays,
10% Analysis of the data to help determining the research strategy,
10% Lead projects and/or major project tasks,
10% Interactions with collaborators within our network and writing of manuscripts for publication
5% Provide guidance and direction to project staff, students and postdocs
Requirements:
Master's Degree in Biochemistry or related field and four years 4 years of experience in related field like: Cryo-electron microscopy, virology assays (pseudotyped virus generation, cellular entry and neutralization assays), protein expression in mammalian cells and purification
Equivalent education and/or experience may substitute for minimum qualifications except when there are legal requirements, such as a license, certification, and/or registration.
Desire:
Expertise in protein and vaccine design, experience in high throughput automation using Beckman Biomek.
Compensation, Benefits and Position Details
Pay Range Minimum:
$99,444.00 annual
Pay Range Maximum:
$122,124.00 annual
Other Compensation:
Benefits:
For information about benefits for this position, visit https://www.washington.edu/jobs/benefits-for-uw-staff/
Shift:
First Shift (United States of America)
Temporary or Regular?
This is a regular position
FTE (Full-Time Equivalent):
100.00%
Union/Bargaining Unit:
UAW Research
