Research Associate II, Discovery BiosciencePurpose & Scope The Research Associate will be an integral member of the Vector Bioscience team and assist in developing, characterizing, and producing AAV vectors. The Research Associate will work at our South San Francisco R&D laboratories, supporting and collaborating with various research and development groups.
Role and Responsibilities - Perform cell culture work, including thawing, maintaining, transfecting, and cryopreserving cell lines
- Production and purification of AAV vectors for various programs
- Collaborate with other teams to acquire and characterize vectors
- Document characterization of vectors and other activities
- Communicate results and timelines to other functional groups
- Collaborate in laboratory management and safety activities
Required Qualifications - Bachelor's degree in a life science, chemical engineering or related discipline with 3+ years of experience or a Master's degree with 1+ years of experience in cell culture and protein purification techniques.
- Proven hands-on experience with sterile technique for handling and growing mammalian cell lines, including maintenance, cell characterization and differentiation, expansion, and banking
- Demonstrated experience with routine molecular biology techniques (cloning, DNA/RNA/protein isolation, digital PCR), plasmid preparation
- Protein expression and purification, and characterization
- Transfection and/or transformation experience with mammalian or bacterial cells.
- Experience with purification and chromatography systems such as the AKTA
- Ability to work both independently and in a team-oriented environment to meet project goals and timelines
- Strong written and verbal communication skills
Preferred Qualifications - Experience working with viruses, especially Adeno-Associated Virus (AAV)
- Industry experience
Location and Working Environment- This position is based in South San Francisco, CA and will require on-site work. This is a highly collaborative and laboratory-based role with reasonably flexible working arrangements.
Salary Range$XXXXXX-XXXXXX (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations.)
Benefits:- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
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