Research Associate, Formulation Development

Pivotal Life Sciences

$65K — $100K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree or higher in a relevant scientific field.
  • 3+ years of experience in pharmaceutical formulation focusing on lipid nanoparticle drug delivery.
  • Proficient in dynamic light scattering, zeta potential measurement, and nanoparticle characterization techniques.
  • Demonstrated strong analytical and problem-solving capabilities.
  • Effective communicator with teamwork skills.
  • Self-motivated and capable of managing multiple tasks.

Responsibilities

  • Develop lipid nanoparticle formulations specifically for gene editing.
  • Conduct experiments to fine-tune formulation parameters like particle size and stability.
  • Enhance production processes to maximize yields and scalability.
  • Troubleshoot and resolve formulation-related challenges.
  • Use analytical techniques to characterize lipid nanoparticles.
  • Support in vitro and in vivo studies to assess formulation efficacy and safety.
  • Collaborate with teams to facilitate the translation of formulations from lab to clinic.

Benefits

  • Competitive salary, equity, and comprehensive benefits.
  • Professional growth opportunities in a collaborative environment.
  • Innovative work culture with a focus on fast-paced research and development.
  • Full benefits package including Medical, Dental, Vision, Life, and Disability insurance, plus a 401k match of 4%, Paid Time Off, and Equity.
Full Job Description
Research Associate, Formulation Development

Location: San Diego, CA

Job Type: Full-Time, Onsite

Job Summary

We are seeking a highly motivated and skilled individual to join our team as a Research Associate in Formulation Development. The successful candidate will be responsible for designing, executing, analyzing, and making recommendations on research protocols for lipid nanoparticle (LNP) drug delivery systems aimed at gene editing. Title level and salary will be commensurate with experience.

Responsibilities
  • Develop lipid nanoparticle (LNP) formulations for gene editing applications.
  • Conduct experiments to optimize formulation parameters such as particle size, encapsulation efficiency, and stability.
  • Optimize production processes to improve yields and scalability.
  • Troubleshoot and resolve issues related to formulation processes.
  • Perform analytical characterization of LNPs using techniques such as dynamic light scattering (DLS), zeta potential measurement, and electron microscopy.
  • Support in vitro and in vivo studies to evaluate the efficacy and safety of LNP formulations.
  • Collaborate with preclinical and clinical teams to ensure successful translation of formulations.
  • Maintain accurate and detailed laboratory records.
  • Prepare technical reports and presentations to communicate findings.
  • Stay current with advancements in LNP technologies and methodologies.


Qualifications
  • Bachelor's degree or higher in Chemistry, Pharmaceutics, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
  • 3+ years of experience in pharmaceutical formulation, with a focus on lipid nanoparticle drug delivery systems.
  • Experience with techniques such as DLS, zeta potential measurement, and other analytical tools used in nanoparticle characterization.
  • Strong analytical and problem-solving skills.
  • Excellent communication and teamwork abilities.
  • Ability to work independently and manage multiple tasks effectively.


Preferred Qualifications
  • GMP production experience.
  • Familiarity with regulatory requirements and quality control in bioprocessing.


Benefits
  • Competitive salary, equity, and benefits package.
  • Opportunities for professional growth and development.
  • Fast paced collaborative and innovative work environment.
  • We offer an exceptional benefits package to include Medical, Dental, Vision, Life, Disability, a 401k Match of 4%, Paid Time Off and Equity.


How to Apply

Interested candidates should submit their resume and a cover letter detailing their relevant experience. To be considered for the role, applicants must be:
  • Eligible to work in the United States for any employer without current or future sponsorship.
  • Able to work onsite in the lab, based on the location listed for the position (either San Diego, CA or Boston, MA). Please check the position listing when you Apply for the location of each role.
  • Direct candidates only and not from a third party, i.e., staffing agency.


Salary Range

$65,000 - $100,000

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