Guardant Health is seeking a high performing Regional Strategic Account Manager, Health Systems to expand adoption of Shield and Guardant’s broader portfolio across prioritized Regional IDNs and Organized Customer Groups. This role leads enterprise growth by building and executing strategic account plans, engaging C/D-suite and senior clinical/operational leaders, and coordinating cross-functional teams to deliver scalable implementation and measurable outcomes. The SAM is a consultative, outcomes-oriented leader who can navigate complex health system environments, drive diagnostic adoption through workflow and integration enablement, and consistently deliver results—while operating with the highest standards of integrity and compliance. Essential Duties and Responsibilities • Develop and execute multi-year strategic account plans across assigned health systems, including stakeholder mapping, opportunity sizing, prioritization, and cross-functional execution rhythms. • Build strong relationships with enterprise decision-makers and influencers (C/D-suite, service line leaders, population health, quality, finance, operations, IT) and align Guardant solutions to strategic priorities. • Drive Shield adoption and scale through health system enablement, including clinical workflow development, EMR integration support, pilot design/execution, metric definition, and enterprise rollout. • Identify gaps in care delivery and operational barriers to adoption; translate insights into solution strategies that support transformative change and measurable impact. • Lead QBRs/MBRs with defined performance metrics to track progress, quantify value, and evolve expansion plans. • Coordinate closely with internal Guardant teams (e.g., Medical, Market Access, Implementation, Informatics/IT enablement, Marketing, Sales Ops, Legal/Compliance) to ensure aligned, compliant execution. • Maintain fluency in market dynamics shaping health system decisions—policy trends, quality frameworks, value-based care progression, and risk-based contracting structures (e.g., ACO/shared savings, capitation/global budgets, bundled payments, Medicare Advantage risk, and commercial value-based contracts). • Consistently meet or exceed goals with strong CRM discipline, forecasting accuracy, teamwork, and contribution to best-practice playbooks. • Represent Guardant Health’s mission, culture, and values to internal and external stakeholders. • Adhere to all Compliance, Regulatory, and Quality Management System (QMS) policies. • Travel up to 50% within territory, with occasional regional or national meetings. • Meet all applicable customer access requirements. Qualifications • 5+ years Account Management at C/D-Suite • Proven experience in strategic/enterprise account management strategy, navigation, and revenue adoption within complex health systems/IDNs and organized customer structures. • Strong background in diagnostics adoption within health systems, including navigating clinical stakeholders, lab/diagnostic pathways, enterprise governance, and multi-site standardization. • Demonstrated success leading cross-functional initiatives and driving progress without direct authority. • Track record of enabling adoption through workflow change and/or EMR-enabled implementation (directly or in partnership with internal teams). • Executive presence, strong business acumen, and ability to translate strategy into measurable execution. • Commitment to compliance, integrity, and collaborative team success. • Highly organized, proactive communicator with advanced project management capabilities. • Proficiency with Microsoft Office (Excel, PowerPoint) and CRM tools (Salesforce.com preferred). AI & Digital Fluency • Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work. Hybrid Work Model:This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies.  Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients. The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Remote - Open Position (USA) Primary Location Base Pay Range: $151,800 - $208,750 Other US Location(s) Base Pay Range: $151,800 - $208,750 If the role is performed in Colorado, the pay range for this job is: $151,800 - $208,750 Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.