OverviewWaters Corporation seeks an innovative and highly motivated
Principal Scientist to join the
Core Separation Team within the Chemistry & Lab Automation (C&LA) Business Unit.
In this role, you will advance liquid chromatography (LC) science by evaluating, developing, and commercializing next-generation chromatographic technologies. As a technical leader, you will collaborate across R&D, engineering, materials science, applications, and product management to transform innovative concepts into successful products.
The ideal candidate combines deep expertise in liquid chromatography with strong scientific leadership and problem-solving skills. This role will help shape future LC column technologies and chromatographic media that deliver meaningful value to customers worldwide.
Responsibilities- Design and execute experiments to evaluate novel LC columns, stationary phases, and sample preparation devices for small-molecule separations.
- Provide technical leadership for cross-functional development programs involving chromatographic science, applications, and method development.
- Collaborate with engineering, materials science, and product teams to develop hypotheses, design studies, and optimize emerging technologies.
- Lead laboratory characterization and performance testing of prototype column products and sample preparation devices, assessing efficiency, robustness, reproducibility, and application suitability.
- Prepare reports and provide internal presentations to summarize scientific findings
- Develop and optimize chromatographic methods supporting technology evaluation, product development, and customer applications.
- Establish analytical methods, product specifications, and quality-control procedures for product launch.
- Drive the transition of new technologies from research through development, manufacturing, and product launch.
- Contribute to intellectual property generation by assisting with invention disclosures and patent applications.
- Work with marketing colleagues and other technical groups across Waters to successfully commercialize new products and to showcase them through publications and presentations at conferences
- Monitor scientific and competitive trends to identify emerging applications, methods and customer needs.
- Maintain laboratory operations and ensure compliance with environmental, health, safety, and quality (EHSQ) requirements.
QualificationsRequired Qualifications- Ph.D. in Chemistry, Biochemistry, Chemical Engineering, or a related field with 5+ years of industrial experience, including leadership of technical projects; or an M.S. degree with 7+ years of relevant industry experience.
- Strong knowledge of liquid chromatographic theory, separation mechanisms, and stationary-phase chemistry.
- Hands-on expertise in liquid chromatography, including the use of mass spectrometric detection.
- Proven experience developing, optimizing, and troubleshooting LC methods.
- Proficiency with HPLC instrumentation, laboratory operations, and instrument maintenance.
- Demonstrated ability to independently lead technical programs and manage multiple priorities.
- Excellent written and verbal communication skills, including experience in giving technical presentations and writing scientific report.
- Strong analytical thinking, scientific curiosity, and commitment to innovation.
- Ability to collaborate and influence effectively across multidisciplinary teams.
Preferred Qualifications- Experience developing or characterizing chromatographic columns, stationary phases, or separation media.
- Experience supporting product development, manufacturing transfer, commercialization, or quality-control activities.
- Knowledge of analytical workflows in pharmaceutical, biopharmaceutical, environmental, food, or related industries.
- Track record of patents, publications, invention disclosures, or scientific presentations.
- Experience applying Design of Experiments (DOE) and data-driven approaches to technology development.
Key WordsChromatography, Liquid Chromatography, HPLC, UHPLC, LC-MS, Separation Science, Method Development, Stationary Phase Chemistry, New Product Development, Product Commercialization, Analytical Chemistry, Mass Spectrometry.
