Roche

Principal Business Manager, Early Clinical Development (ECD)

Roche • $136K — $252K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree required; project management or process improvement certifications preferred (PMP, Six Sigma, Agile, Change Management).
  • 5–10 years in business management, cross-functional initiatives, or operations programs, preferably in clinical development.
  • Expertise in strategic planning, project management, business process improvement, and team facilitation.
  • Proactive problem solver with a knack for challenging standard processes and proposing creative solutions.
  • Strong written, oral, and presentation skills with a proven ability to build productive cross-functional relationships.
  • Demonstrated ability to develop and execute change management and communication strategies.

Responsibilities

  • Foster team alignment and build networks across functions and external partners to achieve key milestones.
  • Drive talent development and engagement programs, including departmental workshops and recognition initiatives.
  • Serve as a thought partner to executive leadership, advising on priorities and driving enterprise strategy.
  • Structure leadership meetings with clear agendas and rigorous follow-up on action items.
  • Oversee annual planning, resource forecasting, budget allocation, and goal setting.
  • Recommend operational strategies to balance innovation with organizational needs.
  • Resolve complex business challenges by mobilizing stakeholders and aligning functional goals.

Benefits

  • Opportunity for professional growth through talent development and engagement programs.
  • Participation in departmental workshops and recognition initiatives.
  • Access to a collaborative work environment with cross-functional teams.
  • Potential for a discretionary annual bonus based on performance.
  • Onsite presence fosters direct engagement with leadership and teams.
Full Job Description

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD. Reporting directly to the ECD Chief of Staff, this role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight, and execution across the department.  This position requires SSF on-campus presence between 3 to 4 times a week based on business demands. 


The Opportunity:


  • Cross-Functional Collaboration: Fosters team alignment and builds networks across functions, enterprise teams, and external partners to achieve key milestones.
  • Talent & Team Engagement: Drives talent development, engagement programs, departmental workshops, and recognition initiatives to foster professional growth.
  • Strategic Leadership Partnership: Serves as a thought partner to executive leadership, advising on priorities, providing constructive challenge, and driving short- and long-term enterprise strategy.
  • Meeting Facilitation & Action Tracking: Structures leadership meetings with clear agendas, concise documentation, and rigorous follow-up on action items.
  • Business & Financial Planning: Oversees annual planning, resource forecasting, budget allocation, and goal setting.
  • Operational Strategy & Innovation: Balances innovation with guardrails, recommending operational strategies to address evolving enterprise needs.
  • Complex Problem Solving: Resolves complex business challenges by mobilizing stakeholders and aligning functional goals with broader organizational priorities.
  • Working Hours: Ability to work over 8 hours/day or 40 hours/week, including early morning or late-night calls, to meet business demands.
  • Rapid Responsiveness: Capacity to respond promptly to emails and phone calls as business needs arise.
  • Physical Capability: Ability sitting or standing for extended periods during back-to-back meetings.
  • Onsite Mobility: Ability to carry up to 10 lbs of materials and travel between campus buildings for meetings and offsites.
  • Travel: Ability to travel domestically and internationally as needed.

Who You Are:


  • Education & Certifications: Bachelor’s degree required; project management or process improvement certifications (PMP, Six Sigma, Agile, Change Management) preferred.
  • Experience: 5–10 years in business management, cross-functional initiatives, or operations programs (clinical development experience preferred).
  • Core Competencies: Expertise in strategic planning, project management, business process improvement, and team facilitation.
  • Problem Solving & Innovation: Proactive problem solver skilled at challenging standard processes, proposing creative solutions, and adapting to fast-changing demands.
  • Communication & Relationships: Strong written, oral, and presentation skills with a proven ability to build transparent, productive cross-functional relationships.
  • Change Leadership: Demonstrated ability to develop and execute change management and communication strategies across the enterprise.

Onsite presence on our South San Francisco campus is expected for at least 3 days a week.


Relocation benefits are not available for this job posting.


The expected salary range for this position based on the primary location of California is $136,100 - $252,700.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.



#ECD

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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