AstraZeneca

Medical Lead - GI Cancer

AstraZeneca • $193K — $289K *
Gaithersburg, MD 20878In-Person
Pharmaceuticals & Biotech
5 - 7 years of experience
Today
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Job Overview by Ladders

Qualifications

  • Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent
  • 5+ years of experience in industry, clinical, or research settings, ideally in oncology or rare diseases
  • 1-3 years of experience in HQ Medical Affairs
  • Proven track record in cross-functional team collaboration
  • Strong written, verbal, and presentation skills
  • Ability to travel nationally and internationally to support medical initiatives

Responsibilities

  • Lead Medical Affairs for the GI oncology franchise, guiding evidence generation and strategic direction
  • Ensure medical accuracy and compliance in promotional and educational materials
  • Establish relationships with advocacy and provider groups to enhance patient care strategy
  • Provide medical guidance on product safety and benefit-risk assessments
  • Collaborate with Medical Science Liaisons to support key accounts and medical planning
  • Work cross-functionally with commercial and scientific teams to deliver patient-centered outcomes

Benefits

  • Flexible in-office work arrangement with a minimum of three days per week
  • Short-term incentive bonus opportunity
  • Eligibility for equity-based long-term incentive program
  • Qualified retirement program (401(k) plan)
  • Comprehensive health benefits including medical, dental, and vision coverage
  • Paid vacation and holidays
  • Paid leaves as per company policies
Full Job Description
In this role, you will set the medical direction for a critical GI oncology franchise, fusing robust evidence with clear strategy to change how patients are treated. You will partner closely with colleagues across the enterprise-from research and safety to field teams and market access-to ensure our science is communicated with integrity, our insights drive action, and our launches and lifecycle plans deliver real impact.

You will join a high-performing, collaborative team that learns fast, moves with purpose, and values both ambition and kindness. With access to cutting-edge research and a deep pipeline, you will have the platform to grow your expertise, influence global standards of care, and see your work make a measurable difference for patients, science, and society.

Accountabilities:
  • Medical Leadership: Lead Medical Affairs for the GI oncology franchise and provide medical leadership to the Core Medical Team, setting direction for evidence generation, launch readiness, and lifecycle strategy that elevates standards of care.
  • Evidence and Information Integrity: Ensure medical accuracy and fair balance of all medical information in promotional and learning materials for internal and external use, maintaining scientific rigor and compliance.
  • External Partnerships: Build credible relationships with advocacy, payer, and provider groups to align on patient needs, inform strategy, and shape scientific exchange that drives adoption of best practices.
  • Safety and Benefit-Risk: Provide medical input into the product safety profile in collaboration with Patient Safety physicians, interpreting emerging data and guiding risk communication and mitigation.
  • Field and Key Account Collaboration: Partner with Medical Science Liaisons and work closely with National Clinical Account Managers to support key accounts, translating insights into targeted medical plans and impactful engagements.
  • Cross-Functional Influence: Work collaboratively with commercial and scientific colleagues to integrate insights, align on priorities, and deliver coordinated, patient-centered outcomes across the franchise.

Essential Skills/Experience:
  • Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or international equivalent
  • A minimum of 5+ years of related work experience in industry, clinical or research institution, preferably in oncology, rare disease, or related experiences
  • 1-3 years in HQ Medical Affairs role
  • A minimum of 3+ years of related work experience in industry, clinical or research institution, preferably in oncology, rare disease, or related experiences
  • Experience in supporting brands or disease area levels in-country, regional, or global organizations is preferred
  • Proven track record of interacting efficiently with both commercial and scientific/medical colleagues
  • Demonstrated ability to work collaboratively in cross-functional teams
  • Ability to travel nationally and internationally
  • Highly developed written, verbal, and presentation skills
  • Travel will be up to ~30% of time.

Desirable Skills/Experience:
  • Solid understanding of FDA requirements
  • Experience in a strategy-setting role within Medical Affairs
  • Experience in navigating sophisticated business challenges
  • Experience in developing and maintaining a network that includes third-party expert
  • Experience in other relevant disease areas of interest through clinical experience, biopharmaceutical experience, or education may be considered
  • Knowledge of relevant Professional Societies and Scientific Medical Experts.
  • Experience with pharmaceutical drug development and Medical/Scientific Affairs

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Call to Action:
If you are ready to lead GI cancer strategy, elevate standards of care, and see your impact reach patients and practice, take the next step and submit your application today.

The annual base pay for this position ranges from $ 193,281 - 289,922 USD. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered include a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors

Date Posted
04-Aug-2026

Closing Date
17-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Pharmaceuticals & Biotech
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ
AZN
* Ladders Estimates

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