LC-MS/MS Toxicology Laboratory Supervisor

LC-MS/MS Toxicology Laboratory Supervisor
Rocky Mountain Laboratories - Draper, Utah

Position

Rocky Mountain Laboratories is seeking an experienced Clinical Toxicology Laboratory Supervisor with hands-on Agilent LC-MS/MS expertise and method development experience to lead our toxicology department in Draper, Utah, part of the Salt Lake City metro area.

This is a working supervisor role in a CLIA-certified, high-complexity toxicology laboratory. You'll combine bench-level technical work - LC-MS/MS method development and validation, instrument operation, and data review - with day-to-day departmental leadership: staff oversight, SOP development, QC program management, and regulatory compliance. You'll serve as the primary technical and operational lead for the toxicology department and act as department representative in the absence of the Lab Manager.

This is a lean, growing laboratory, not a large reference-lab environment. Our team owns the full testing process end-to-end rather than specializing in a single segment. The right person has personally carried clinical toxicology testing across the entire workflow - sample prep, instrument operation and maintenance, method development and validation, data review, QC, and result release - and is comfortable both doing the work and leading others who do.

Job Type: Full-time, W2
Schedule: Monday-Friday | 8:00 a.m.-4:30 p.m. | Day shift
Salary: $130,000-$150,000 annually
Location: Draper, UT (Salt Lake City metro) - reliable commute or relocation required before start date
Start Date: As soon as the right candidate is found

Responsibilities:

• Supervise daily toxicology laboratory operations to ensure accurate, timely, and compliant high-complexity testing
• Operate, calibrate, maintain, troubleshoot, and optimize Agilent 6460 triple quadrupole LC-MS/MS instrumentation and related platforms
• Develop, validate, and implement new analytical methods for clinical toxicology panels including drugs of abuse (DOA), pain management, and therapeutic drug monitoring (TDM)
• Lead method verification, troubleshooting, and continuous optimization of existing assays
• Oversee sample preparation workflows for urine and oral fluid specimens
• Develop, implement, and maintain Standard Operating Procedures (SOPs) for validations, clinical testing, and regulatory compliance
• Review, interpret, and authorize release of patient test results using Agilent MassHunter and other laboratory software in accordance with laboratory policies and CLIA standards
• Manage quality control (QC) and quality assurance (QA) programs; investigate out-of-range results and deviations; implement and document corrective actions
• Monitor workflow, prioritize testing queues, and allocate staff resources to meet turnaround time expectations
• Train, mentor, and evaluate laboratory staff; develop and administer competency assessments and provide ongoing technical guidance
• Serve as CLIA General Supervisor for the toxicology department, ensuring full compliance with high-complexity testing standards, OSHA safety requirements, and other applicable regulations
• Support internal inspections, CAP accreditation activities, audits, and regulatory readiness
• Collaborate cross-functionally with Chemistry, Molecular, Client Services, and other departments to resolve operational and testing issues
• Drive continuous improvement initiatives related to workflow efficiency, quality outcomes, and cost reduction
• Ensure proper handling, storage, and disposal of hazardous and biological materials
• Serve as acting department leader in the absence of the Lab Manager
• Perform other duties as assigned

Required Qualifications:

• Bachelor of Science or higher in chemistry, biology, clinical laboratory science, medical laboratory science, or a closely related field
• Minimum 3 years of documented hands-on clinical toxicology experience in a CLIA-certified high-complexity laboratory, including drugs of abuse (DOA), pain management panels, or therapeutic drug monitoring (TDM), and including direct involvement in method development or validation
• Demonstrated experience independently performing the complete LC-MS/MS testing workflow - from sample preparation through instrument maintenance, method validation, data review, and result release - rather than a single specialized segment
• Recent hands-on experience operating, maintaining, and troubleshooting Agilent 6460 triple quadrupole LC-MS/MS or equivalent Agilent 6400-series instrumentation, including proficiency with Agilent MassHunter for data acquisition, analysis, and reporting
• Documented experience in LC-MS/MS method development and validation in a clinical or regulated laboratory setting
• Proficiency with sample preparation techniques, including dilute-and-shoot, solid-phase extraction (SPE), and liquid-liquid extraction (LLE)
• Strong knowledge of quality assurance, quality control principles, and corrective action processes
• Demonstrated knowledge of CLIA high-complexity testing regulations, OSHA safety requirements, and regulatory compliance
• Excellent organizational, analytical, and problem-solving skills
• Strong written and verbal communication skills
• Ability to manage multiple priorities while maintaining accuracy and compliance
• Other duties as assigned

Preferred Qualifications:

• 3-5+ years of clinical toxicology laboratory experience, including at least 1 year in a supervisory, lead, or certifying scientist capacity
• Experience developing or delivering competency assessments for laboratory staff
• Experience with Beckman Coulter AU 480/680 or equivalent Beckman Coulter AU-series chemistry analyzers (e.g., AU400, AU5800)
• Experience with additional LC-MS/MS platforms (e.g., SCIEX, Shimadzu, Thermo Fisher)
• Experience supporting CAP accreditation, laboratory audits, and regulatory inspections
• Familiarity with Laboratory Information Systems (LIS) and electronic reporting workflows
• Ability to design and deliver technical training programs for laboratory staff
• Experience with high-throughput batch processing workflows in a clinical toxicology environment
• ASCP MLS(ASCP), AMT MT, NRCC, or other relevant certification
• Master's degree in chemistry, toxicology, clinical laboratory science, or a related field

Benefits for full-time W2 Team Members:
Benefits begin 60 days after the first full month of full-time employment.

• Health, Dental, and Vision Insurance
• Paid Time Off (21 days annually for full-time team members)
• 7 Paid Holidays
• 401(k) with 50% Company Match up to 6%
• Health Savings Account (HSA)
• Short-Term & Long-Term Disability (RML covers 60% of STD premium)
• Voluntary Life and AD&D Insurance
• 100% Company-Funded Employee Assistance Program (EAP)

Application Deadline: Applications are reviewed on a rolling basis, and the position may be filled before any stated deadline

If you meet the above qualifications and are interested in joining our team, please submit your resume for consideration. We look forward to hearing from you!

At Rocky Mountain Laboratories, we prioritize the care and well-being of our team members.