Medical degree (MD or equivalent) or higher degree in life sciences (e.g., PharmD, PhD, MSc)
12+ years of experience in pharmacovigilance (PV) and clinical research/development
7+ years in senior Patient Safety leadership roles
7+ years of executive leadership experience with large teams
Proven enterprise-first mindset with strategic influence
Extensive engagement with Tier-1 global Health Authorities
Responsibilities
Lead the Affiliate Patient Safety strategy and collaborate with cross-functional leaders
Maintain oversight of the local PV system for compliance and operational efficiency
Ensure product safety launch readiness and align global safety solutions
Lead safety communication strategies for healthcare professionals and stakeholders
Drive collection and analysis of safety insights using digital solutions
Provide leadership to the US Patient Safety Leadership Team and oversee talent development
Benefits
Relocation benefits available
Discretionary annual bonus based on performance
Comprehensive benefits package as detailed in the provided link
Full Job Description
The Head of US Patient Safety is accountable for the overall strategic direction, operational execution, and holistic performance of the PV system for the USA, ensuring full alignment with International Patient Safety (IPS) priorities and business needs. Operating in close partnership with Genentech, the Head of US Patient Safety serves as the primary steward of the affiliate PV system and safety risk management.
The Opportunity:
In this role, core responsibilities will include:
Strategy: Lead the Affiliate Patient Safety strategy, collaborating with cross-functional leaders to prioritize initiatives that maximize patient and business impact. Additionally, serve on the IPS Leadership Team to co-own the strategic vision, governance, and collective performance of the broader IPS organization.
PV System: Maintain holistic oversight of the local PV system to ensure strict compliance, operational efficiency, and inspection readiness, thereby safeguarding the company’s license to operate.
Safety Risk Management: Ensure product safety launch readiness, aligning global safety solutions with therapeutic strategies and driving local risk minimization efforts that improve patient outcomes.
Safety Communication: Lead strategies to communicate and educate on safety risks in context, ensuring transparent and timely safety communications to healthcare professionals, patients, and external stakeholders, in partnership with US Medical and other functions.
Safety Insights: Drive the systematic collection, analysis, and sharing of safety insights aligned with disease area goals, leveraging digital solutions and real-world evidence as appropriate.
People Leadership & Talent Pipeline: Provide solid-line leadership to the US Patient Safety Leadership Team, with overarching talent oversight, succession planning, and capability building across all US safety staff.
Who you are:
Medical degree (MD or equivalent) or higher degree in life science discipline (e.g., PharmD, PhD, MSc)
Minimum of 12 years of experience in PV, clinical research/development, including 7+ years in senior Patient Safety leadership roles across complex regional or global environments.
Minimum of 7 years of executive people leadership coaching, developing, and engaging large multi-layered teams and networks of leaders.
Proven track record of operating with an enterprise-first mindset, demonstrating behaviors that consistently drive impact, influence strategy, and build capabilities beyond assigned regional borders.
Executive presence and recognized authority influencing senior leadership across local and global organizations.
Extensive experience engaging with major Tier-1 global Health Authorities and shaping international PV ecosystems
Relocation benefits are available for this posting
The expected salary range for this position based on the primary location of California is $282,000 - $523,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
About Roche
Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.