Director, Screening and High Content Analysis

Rocket Mortgage

$120K — $150K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 5-7 years of experience in high-content imaging or phenotypic screening
  • Demonstrated success in designing automated screening campaigns
  • Proficient in image analysis tools such as CellProfiler and Python-based platforms
  • Experience with AI/ML methods applied to biological data
  • Background in handling complex biological systems like organoids
  • Proven leadership in academic, biotech, or pharmaceutical settings
  • PhD in bioengineering, computational biology, neuroscience, or related field

Responsibilities

  • Establish and lead a high-content imaging and screening platform
  • Design automated workflows for organoid and cell-based assays
  • Develop and optimize phenotypic assays and analysis pipelines
  • Integrate AI/ML techniques for image analysis
  • Manage and scale screening pipelines for robustness and reproducibility
  • Oversee a multidisciplinary team of scientists and analysts
  • Collaborate on screening campaigns targeting drug discovery

Benefits

  • Comprehensive health and wellness benefits for you and your family
  • Individualized support for your lifestyle and personal needs
  • Focus on employee well-being and peace of mind
  • A commitment to fostering innovation and growth within the team
  • Access to various perks to enhance work-life balance
Full Job Description

As the Director, Screening and High Content Analysis, you will lead the development and execution of NGNRI’s high-content screening platform, driving target discovery and therapeutic development using advanced organoid and cell-based models.

This role will design and scale automated screening workflows that integrate high-content imaging, quantitative image analysis, and data science approaches, including AI-driven methods. As a scientific and technical leader, you will ensure seamless integration of screening capabilities with NGNRI’s broader research platforms and strategic priorities.

This is a key leadership position with a clear mandate: to build and manage robust, high throughput screening and analysis systems that accelerate the discovery of therapeutic targets and compounds for NF1 and related neurological disorders.

About therole

  • Establish and lead NGNRI’s high-content imaging and screening platform

  • Design and implement automated screening workflows for organoid and cell-based assays

  • Develop and optimize imaging assays, phenotypic readouts, and quantitative analysis pipelines

  • Integrate AI/ML-based approaches for image analysis and pattern recognition

  • Ensure scalability, robustness, and reproducibility of screening pipelines

  • Collaborate closely with the Head of Cell Culture and Organoids to align biological models with screening requirements

  • Recruit, train, and manage a multidisciplinary team (biologists, imaging scientists, data analysts)

  • Oversee data management, storage, and analysis pipelines, ensuring accessibility and integrity

  • Partner with internal and external researchers to design screening campaigns for target identification and drug discovery

  • Continuously evaluate emerging technologies in imaging, automation, and computational analysis

  • Contribute to interpretation of screening results and downstream validation strategies

  • Ensure compliance with relevant regulatory, data governance, and ethical standards

Aboutyou

  • High integrity and commitment to scientific excellence

  • Innovative and technology-driven mindset

  • Strong leadership and team development skills

  • Collaborative and interdisciplinary approach

  • Detail-oriented with strong organizational skills

  • Adaptable and results-driven

Preferred Qualifications

  • Significant experience in high-content imaging, phenotypic screening, or related

  • fields

  • Proven track record in designing and executing automated screening campaigns

  • Expertise in image analysis tools and platforms (e.g., CellProfiler, ImageJ, Python

  • based pipelines, or equivalent)

  • Experience with AI/ML approaches applied to biological imaging data is highly

  • desirable

  • Experience working with complex biological systems such as organoids or stem cell

  • derived models is a strong asset

  • Demonstrated leadership experience in academic, biotech, or pharmaceutical

  • environments

  • Strong analytical and problem-solving skills

  • Excellent communication and cross-functional collaboration abilities

  • Experience managing large datasets and computational workflows

  • Familiarity with drug discovery pipelines is advantageous

  • PhD in bioengineering, computational biology, neuroscience, cell biology, or related discipline

Whatyoullget

Our team members fuel our strategy, innovation and growth, so we ensure the health and well-being of not just you, but your family, too! We go above and beyond to give you the support you need on an individual level and offerall sorts of ways to help you live your best life. We are proud to offer eligible team members perks and health benefits that will help you have peace of mind. Simply put: We7ve got your back. Check out our full list ofBenefits and Perks.

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