Roche

Director, Portfolio Strategy & Governance.

Roche$160K — $297K *
Finance & Insurance
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor’s degree in Finance, Business, Operations, or related field; MBA/MS preferred
  • 10+ years of experience in portfolio or program leadership, strategy, or operations
  • Demonstrated experience in evolving portfolio operating models
  • Proven track record in technology and process transformation governance
  • Ability to connect strategy to execution with operating structures
  • Experience in establishing outcome measures linking investments to business value
  • Strong executive presence to influence senior stakeholders

Responsibilities

  • Define and evolve the Digital Finance portfolio strategy
  • Design a structured intake and prioritization approach for opportunities
  • Own the end-to-end portfolio view, including risks and investment needs
  • Establish and lead governance forums for decision-making
  • Create mechanisms for managing cross-portfolio dependencies and risks
  • Establish an outcome-based performance and value realization framework
  • Serve as a strategic partner to business leaders, translating complex data into clear insights

Benefits

  • Comprehensive benefits package
  • Opportunities for professional development
  • Access to wellness programs
  • Flexible work arrangements
  • Supportive company culture promoting collaboration
Full Job Description

Director, Portfolio Strategy & Governance

The Opportunity:

The Director, Portfolio Strategy & Governance will shape and lead the portfolio operating model for Digital Finance, creating the transparency, prioritization, governance, and accountability needed to translate digital strategy into measurable business outcomes.

This leader will own the end-to-end portfolio strategy and governance framework across a diverse portfolio spanning enterprise platforms and ERP stabilization, data and analytics, AI, automation, process optimization, and data governance. Working across Finance, technology, data, and global teams, the Director will establish how opportunities are evaluated and prioritized, how investments and capacity are aligned to strategic priorities, and how progress, risks, dependencies, and value are surfaced to leadership.

This role requires a leader who can move fluidly between strategy and execution - designing the portfolio operating model while ensuring governance mechanisms, decision forums, and operating rhythms translate into disciplined execution, adoption, and measurable value. The Director will lead primarily through influence, creating alignment and accountability across a highly matrixed enterprise environment.

Key Roles & Responsibilities:


Portfolio Strategy & Prioritization
  • Define and evolve the Digital Finance portfolio strategy and operating model, ensuring the portfolio remains aligned to business priorities and enterprise direction.

  • Design and lead a structured intake and prioritization approach for capturing, triaging, scoring, and approving opportunities, balancing strategic value, demand, risk, dependencies, and available capacity.

  • Own the end-to-end portfolio view, including roadmap, milestones, interdependencies, resourcing, risks, investment needs, and key decisions.

  • Partner with leaders to make portfolio trade-offs and ensure resources and investments are focused on the highest-value priorities.

Governance & Operating Model
  • Establish and lead governance forums, portfolio reviews, intake councils, escalation pathways, decision rights, and decision logs to enable timely, transparent decision-making.

  • Define portfolio and delivery standards, including expectations for documentation, status reporting, templates, operating cadences, and, where appropriate, agile or sprint-based practices.

  • Create clear mechanisms for managing cross-portfolio dependencies, risks, issues, and decisions, driving resolution and accountability across workstreams.

  • Ensure major changes and portfolio decisions are documented with the appropriate traceability to support internal controls, compliance, and audit readiness.

Performance & Value Realization
  • Establish an outcome-based portfolio performance and value realization framework that connects initiatives to measurable business outcomes.

  • Define and track relevant measures such as time savings, cycle-time reduction, error reduction, adoption, service-level improvements, and other agreed business outcomes.

  • Support portfolio-level business case and investment tracking while maintaining visibility into spend across contractors, vendors, tools, and other portfolio investments.

  • Use portfolio insights to identify delivery trends, risks, capacity constraints, and opportunities to improve execution and realized value.

Executive & Cross-Functional Leadership

  • Serve as a strategic partner to Digital Finance and business leaders, translating complex portfolio information into clear insights, choices, and recommendations.

  • Coordinate across Finance, IT, data governance, architecture, global teams, and other enterprise partners to maintain alignment with standards, roadmaps, and governance cadences.

  • Partner with change, communications, and business owners to ensure effective rollout, training alignment, adoption, and sustained outcomes.

  • Lead through influence by setting the operating cadence, coaching workstream leads, facilitating decisions, and driving accountability across matrixed teams while fostering transparency and disciplined execution.

Who You Are:

  • Education: Bachelor’s degree in Finance, Business, Operations, Industrial Engineering, Information Systems, or a related field; MBA/MS preferred.

  • Experience:10+ years of progressive experience in portfolio or program leadership, enterprise transformation, strategy and operations, transformation governance, enterprise PMO, finance transformation, or a related discipline.

  • Portfolio leadership: Demonstrated experience building or materially evolving portfolio operating models, including intake, prioritization, governance forums, decision rights, capacity planning, and portfolio-level performance management.

  • Transformation breadth:Proven track record leading or governing complex portfolios that span technology and process transformation, such as enterprise platforms/ERP, data and analytics, automation, AI, or operating-model change.

  • Strategic and operational leadership: Ability to connect enterprise strategy to execution while creating the structures, operating rhythms, and accountability needed to deliver outcomes.

  • Value orientation: Experience establishing outcome measures and connecting portfolio investments and delivery performance to business value and adoption.

  • Stakeholder leadership: Strong executive presence with demonstrated ability to facilitate decisions, influence senior stakeholders, navigate competing priorities, and build alignment across functions without relying on direct authority.

  • Enterprise environment: Experience operating in complex, matrixed organizations; experience in regulated or controlled environments with strong documentation, traceability, and compliance requirements is preferred.

  • Certifications: PMP, PgMP, SAFe, Prosci, or equivalent portfolio/program/change certification is valued but not required.

Location: This position is based in South San Francisco, CA.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of San Francisco, CA is $160,300- $297,700. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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