Natera

Director of Data Science and Bioinformatics

Natera$178K — $222K *
US-AnywhereRemote in United States
Healthcare
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Master's or Ph.D. in a quantitative field (Biostatistics, Bioinformatics, etc.)
  • 10+ years in Data Science or Bioinformatics, 5+ years in people management
  • Hands-on experience with AWS cloud infrastructure for NGS
  • Ability to identify gaps and drive infrastructure execution independently
  • Strong communication skills for cross-functional alignment
  • Proven track record in bioinformatics talent development and pipeline delivery

Responsibilities

  • Define and build the Bioinformatics function within Data Science
  • Establish and enforce quality standards for algorithms and pipelines
  • Architect scalable AWS-based infrastructure for bioinformatics
  • Implement MLOps tooling for reliable clinical production deployment
  • Collaborate with teams across research, engineering, and quality
  • Lead and mentor a high-performing team of bioinformaticians and data scientists
  • Cultivate technical expertise to support product expansion in Women's Health and Organ Health

Benefits

  • Remote work opportunity
  • Opportunity to lead and shape a growing team
  • Focus on innovative genomics-based algorithm development
  • Engagement in cross-disciplinary collaborations
  • Potential to influence product development in women's and organ health sectors
Full Job Description
This is an exciting opportunity to lead and grow the Data Science and Bioinformatics function supporting Natera's Women's Health and Organ Health product portfolios. In this role, you will build the bioinformatics capability within the Data Science development team, establish scalable AWS cloud infrastructure, and ensure the quality and reproducibility of the genomic algorithms powering our clinical products.

PRIMARY RESPONSIBILITIES:

Strategy and Vision
  • Build and define the Bioinformatics function within the Data Science development team, identify technical tooling gaps, and execute a roadmap to advance genomics-based algorithm development.
  • Establish and enforce pipeline and algorithm quality standards, including review processes, validation frameworks, and documentation practices

Infrastructure and Automation
  • Own and architect scalable AWS-based data science and bioinformatics infrastructure, ensuring quality, reproducibility, and reliable deployment of Next-Generation Sequencing (NGS) algorithms.
  • Implement MLOps tooling and automated validation frameworks to support reliable algorithm deployment into clinical production.

Cross-Functional Collaboration
  • Partner with Research, Product Development, Laboratory Operations, Engineering, and Quality teams to implement stable, scalable pipelines and support successful productization

Team Leadership
  • Lead, mentor and hire a high-performing team of bioinformaticians and data scientists, establishing technical quality standards and clear operational ownership.
  • Build technical depth within the team to support expanding product roadmaps across Women's Health and Organ Health.

QUALIFICATIONS:
  • Master of Science or Ph.D. in a quantitative technical discipline (Biostatistics, Bioinformatics, Computer Science, Physics, Applied Mathematics, or equivalent).
  • Minimum of 10 years of experience in Data Science or Bioinformatics, with at least 5 years of direct people management experience leading technical teams.
  • Hands-on experience architecting AWS cloud infrastructure for data-intensive bioinformatics workloads and NGS pipeline execution.
  • Demonstrated ability to identify capability gaps independently, build scalable infrastructure, and drive execution without waiting for formal structure.
  • Strong communicator who builds cross-functional alignment across Research, Engineering, and Quality teams through technical clarity, direct engagement, and data-driven reasoning.
  • Track record of developing bioinformatics talent and delivering computational pipelines that support commercial product development.

PREFERRED QUALIFICATIONS:
  • Experience developing software and pipelines within regulated environments (CLIA, FDA, or ISO framework).
  • Experience with MLOps frameworks and pipeline tools (MLflow, Nextflow, WDL, Docker).
  • Advanced knowledge of statistical inference, machine learning, and genomic data processing.


The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.

Remote USA

$178,200-$222,800 USD

About Natera

Natera is a biotechnology company that focuses on genetic testing and diagnostics. The company's products are designed to help diagnose and treat genetic diseases, cancer, and other conditions. Natera's pipeline includes products for reproductive health, oncology, and organ transplantation. The company was founded in 2003 and is headquartered in San Carlos, California.
Learn more about Natera
Size
2,670 employees
Market Cap
$4.5 billion
Industry
Net Income
-$229.7 million
Founded
2004
5 Year Trend
+24.1%
Revenue
$391 million
NASDAQ

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