Nurix

Director, IT Infrastructure & Operations

Nurix$260K — $300K *
Pharmaceuticals & Biotech
11 - 15 years of experience
Job Overview by Ladders

Qualifications

  • 12+ years in technology services leadership, with 5+ years at Director or Senior Director level.
  • Experience leading cohesive multi-function IT services, including infrastructure and cybersecurity.
  • Ability to collaborate with CISO on policies while executing operationally.
  • Proficient in AWS and Microsoft Entra/Microsoft 365.
  • Familiar with scientific and machine learning computing infrastructures.
  • Proven track record managing and consolidating managed service providers.
  • Background in regulated industries (biotech, healthcare, etc.).
  • Bachelor's degree or equivalent experience.

Responsibilities

  • Consolidate the managed service provider portfolio for infrastructure, security, and help desk functions.
  • Build and develop a cybersecurity operations team from current resources.
  • Establish governance for alignment between research and IT infrastructure.
  • Oversee an identity and access management program.
  • Enhance overall service experience and improve vendor management practices.

Benefits

  • Opportunities for professional growth and leadership in a critical IT role.
  • Collaborative work environment with a strong team orientation.
  • Engagement with cutting-edge technology in the biotech sector.
  • Direct impact on critical infrastructure and operational efficiencies.
Full Job Description
About the role

This is the operating leader for IT infrastructure and operations at Nurix, reporting to the SVP of Information Technology. You will own the function end to end: infrastructure, cybersecurity operations, end user services, and IT service management as one integrated scope. You partner with a fractional CISO on security strategy and policy while owning the operational execution. You work closely with the IT business partner leaders who own the application portfolios and partner directly with R&D and the broader scientific organization on their infrastructure needs.

You lead a team that spans enterprise architecture, system administration, and cybersecurity operations, with the service desk delivered through a mix of staff and managed service providers. You will manage both individual contributors and managers from day one. You set the standards and delegate delivery across this hybrid team of internal staff and managed service providers, empowering the people below you rather than running their queues, to support a fast-moving enterprise.

What you'll do

In your first year you will:
  • Consolidate the managed service provider portfolio across infrastructure, security, and the help desk into a smaller, more accountable set of partners.
  • Build a cybersecurity operations function from current contractor and MDR coverage.
  • Establish a governance model with research and scientific computing, and bring research infrastructure into IT alignment. Working with the enterprise architect, inventory and remediate AWS systems: ParallelCluster and other HPC, container platforms (EKS, ECS), SageMaker, and identity bridges.
  • Own a formal identity and access management program, including clean handoffs to IT operations and the business partner teams.
  • Refresh the service experience end to end and raise vendor management discipline as scope grows.

Requirements:
  • 12+ years of progressive technology services leadership, including 5+ years at the Director or Senior Director level.
  • Direct experience leading multi-function technology services (infrastructure, cyber operations, and ITSM) as one integrated scope rather than separate towers.
  • Comfort partnering with a CISO or fractional CISO on policy while owning operational execution. We are looking for an operator who builds security in partnership, not someone who pushes controls through operations.
  • Deep experience across AWS plus the Microsoft Entra and Microsoft 365 stack.
  • Familiarity with the infrastructure behind scientific and ML computing, AWS ParallelCluster and HPC, SageMaker, EKS and ECS, and DevOps and infrastructure-as-code practices, at a level sufficient to set standards and partner credibly with the scientific organization.
  • A measurable track record managing a managed service provider portfolio, including real consolidation or vendor transitions with accountability for outcomes.
  • Experience building out infrastructure in fast-moving, resource-constrained environments.
  • Experience in a regulated industry (biotech, pharma, medical device, healthcare, financial services, or comparable).
  • Bachelor's degree or equivalent practical experience.

Nice to have
  • Biotech or pharmaceutical industry experience.
  • Support for an FDA Pre-Approval Inspection or BIMO inspection in an IT or security capacity.
  • Experience standing up a security operations function from contractor or MSP coverage.
  • Partnership with a separate scientific computing organization (informatics, bioinformatics, cheminformatics, machine learning).
  • Hands-on with an MDR provider such as RedCanary, Kroll, or Arctic Wolf.
  • Jira Service Management or ServiceNow at scale.
  • Public company SOX IT general controls experience.

Fit with Nurix Culture and Values
  • Strong team orientation; highly collaborative
  • Ability to function in a dynamic environment
  • Solutions and results-oriented focus
  • Hands-on approach; resourceful and open to diverse points of view

Salary Range: $ 260K - $300K plus bonus and equity

Location: Brisbane, CA - Onsite

About Nurix

Nurix Therapeutics is a biotechnology company that is focused on the discovery, development, and commercialization of small molecule therapies that modulate the ubiquitin proteasome system (UPS) for the treatment of cancer and other diseases. The company's proprietary drug discovery platform is based on the use of DNA-encoded libraries (DELs) to identify small molecules that selectively bind to E3 ligases, which are key enzymes in the UPS. Nurix's lead drug candidate, NX-2127, is a first-in-class small molecule inhibitor of the CBL-B E3 ligase that is being developed for the treatment of solid tumors and hematological malignancies. The company was founded in 2013 and is headquartered in San Francisco, California.
Learn more about Nurix
Size
135 employees
Market Cap
$486 million
Industry
Net Income
-$43.2 million
Founded
2009
Revenue
$17.8 million
NASDAQ

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