AbbVie

Director, Computational HitGen / LeadGen Team Lead

AbbVie$160K — $190K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's or Master's degree in a science-related field with extensive experience (18+ or 16+ years respectively) or PhD with 10+ years in a relevant area.
  • Proven coaching, mentoring, and people management experience.
  • Demonstrated ability to set and drive strategy within a global team context.
  • Experience leading multiple, complex research initiatives.
  • Knowledge of modern computational techniques for drug discovery.
  • Excellent communication skills, with a focus on data-driven decision making.
  • Strong analytical skills with the ability to provide creative solutions individually and collaboratively.

Responsibilities

  • Lead development of innovative methods and workflows for AbbVie's small molecule portfolio.
  • Identify gaps for computational predictions in collaboration with small-molecule leadership.
  • Advance drug discovery expertise through collaboration with cross-disciplinary teams.
  • Direct the HGLG team to deliver tools and workflows that meet hit/lead criteria.
  • Guide team in benchmarking experiments for model performance.
  • Establish effective processes for selecting project-specific approaches.
  • Build CDD's reputation by providing expert advice and maintaining presence in the scientific community.

Benefits

  • Comprehensive benefits package including vacation, holidays, and sick leave.
  • Medical, dental, and vision insurance offered.
  • 401(k) plan for eligible employees.
  • Participation in long-term incentive programs.
Full Job Description
Job Description

Overview:

This position brings an opportunity to make innovative contributions that will define how AbbVie leverages AI-native drug discovery across our small molecule portfolio. Reports to Head of Computational Drug Discovery (CDD) and will lead the computational HitGen/LeadGen (HGLG) team. Will implement and enable close collaboration between members of the HGLG team and Drug Discovery partners across the AbbVie community. Must possess a strong track record leveraging modern computational and property-based drug design tools to deliver programs across the phases of a small molecule drug discovery pipeline. The ideal candidate will bring strong experience from across the drug discovery lifecycle from having worked on a broad range of diverse campaigns, and an established external footprint and network. Past experience will have included mentorship of early/mid-career scientists in matrixed and/or direct reporting relationships, with demonstrated ability to lead and influence through cross-functional collaboration.

Responsibilities:

Provide strategic thought leadership to amplify CDD's impact on the small molecule pipeline:
  • Lead development of a cohesive collection of cutting-edge methods and workflows, to comprehensively address AbbVie's small molecule portfolio needs (methods for predicting binding affinities of diverse chemotypes, for predicting pharmacological properties for diverse chemotypes (PK parameters, etc.), and for rapidly sampling both enumerated and AI-generated chemical spaces
  • Work closely with the small-molecule leadership teams to identify and address gaps where computational predictions are needed
  • Advance drug discovery expertise across CDD and collaborate with cross-disciplinary teams from R&D and Information Research to advance programs and ensure computational capabilities are best implemented across programs

Direct activities of the HGLG Team to enable program-level decision making:
  • Across AbbVie's early-stage small molecule portfolio, provide leadership and guidance that will deliver computational tools and workflows to achieve desirable hit/lead criteria. Role will be integral for ensuring alignment across functions and with the longer-term organizational and broader AI-native drug discovery strategies
  • Guide HGLG team members in benchmarking experiments to evaluate models' performance and domain of applicability for AbbVie's small molecule portfolio
  • Establish processes for selecting specific approaches that best suit project needs

Build CDD's reputation for impact:
  • Proactively demonstrate leadership by providing expert advice and shared knowledge with direct reports, peers, and senior management
  • Present program updates and research strategies to functional and non-functional leaders as well as potential and existing partners
  • Maintain awareness of emerging literature and science in the field and author scientific disclosures/publications
  • Maintain scientific presence outside AbbVie with appropriate publication and conference abstract submission highlighting innovative learnings in AI-native drug discovery


Qualifications
  • Bachelor's Degree or equivalent education in science-related field with extensive (typically > 18 years) of related work; Master's Degree or equivalent education with extensive (typically > 16 years) of related work; PhD in Science or related field with typically 10+ years of related work experience
  • Demonstration of successful coaching/mentoring and people management
  • Demonstration of setting and driving strategy, in the context of leading a global team
  • Highly organized and self-directed, experience leading multiple complex simultaneous research programs or initiatives
  • Knowledge and experience in modern computational approaches for drug discovery
  • Excellent written and verbal communication, as well as critical evaluation and data-driven decision making
  • Strong analytical and problem-solving skills with demonstrated ability to think critically and creatively, and provide solutions both individually and collaboratively with internal experts
  • Proven team leadership and management abilities, including experience mentoring, guiding, supervising, and developing scientific personnel with various backgrounds and training levels
  • Highly collaborative, team-oriented, and considerate of the needs of others
  • Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners
  • Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued; willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view


Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

About AbbVie

AbbVie develops pharmaceuticals and medical devices. They provide products and services to therapeutic areas including immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology.

AbbVie Careers

Joining AbbVie means becoming part of a global team dedicated to making a remarkable impact on patients' lives. At AbbVie, our employees are united in the pursuit of groundbreaking innovation and are committed to transforming the future of healthcare with leading-edge science.

Work You’ll Do

At AbbVie, you’ll collaborate with some of the brightest minds in the industry to solve challenging problems that have a high impact on society. Our culture fosters growth and embraces leadership and diversity training, ensuring that every team member can thrive.

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AbbVie offers a wide range of job opportunities and career paths, providing a platform where professionals can propel their careers forward. From research and development to marketing and sales, the potential to make a significant impact is limitless.

Internship Programs

Kickstart your career with an AbbVie internship. Our programs provide invaluable industry experience and a chance to develop essential skills in a real-world setting. Interns at AbbVie are considered integral members of the team and are given tasks that are both challenging and rewarding.

Professional Growth and Development

We believe in nurturing our team's professional growth through comprehensive training programs, leadership development opportunities, and continuous learning. Our commitment to your career growth is reflected in our robust offerings that enhance your skills and knowledge.

Benefits and Culture

AbbVie is dedicated to supporting our employees' well-being both inside and outside of work. Our benefits package includes health, financial, and social benefits that are designed to support the diverse needs of our employees. Our inclusive culture encourages collaboration and innovation, fostering a workplace where all can excel.

Hiring Process

Our hiring process is designed to ensure a match that will be beneficial both for the company and for your career aspirations. From resume submission to interview, each step is an opportunity to showcase your skills and fit with the AbbVie team.

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At AbbVie, networking doesn’t just enhance your career; it propels it. We encourage our employees to engage internally and externally to build relationships that foster personal and professional growth.

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Learn more about AbbVie
Size
50,000 employees
Market Cap
$288.5 billion
Industry
Net Income
$4.6 billion
Founded
2013
5 Year Trend
+17%
Revenue
$45.8 billion
NASDAQ

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