JOB SUMMARY
The Clinical Genomics Scientist analyzes clinical genetics data, curates variants and genes, and summarizes findings for clinical reports. Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and software platforms.
The Clinical Genomics Scientist position is a remote work opportunity, with daily huddles, clear objectives, and flexible scheduling. Minimal on-site time at the headquarters in Houston, TX may be required. Come join our team from the comfort of your home office!
KEY RESPONSIBILITES
- 50%: curation of variants, genes, and gene-disease correlations following ACMG guidelines, using our robust internal dataset, online resources, and published literature
- 30%: analyzing clinical genomics data, including next-generation sequencing, Sanger sequencing, metabolomics, and chromosomal microarray
- 10%: clinical report drafting
- 10%: validation, process refinement, presenting findings at meetings, and performing other duties as needed
- Performs other job-related duties as assigned.
- Adheres to Code of Conduct as outlined in the Baylor Genetics' Compliance Program.
QUALIFICATIONS
- Knowledge of genomic variation and its relationship to human disease
- Knowledge of literature curation methodologies
- Knowledge of variant detection, molecular mechanisms of disease, functional assays, and computational analysis
- Technical expertise in clinical medicine, genetics, genomics, or molecular biology
- Experience with data quality assessment
- Excellent verbal and written communication skills
- Proficiency in communicating an understanding of genetics details
- Knowledge of principles and practices of data analysis as applied to experimental results
- Experience in the application of ontologies for medical/biological annotation
- An understanding of bioinformatics analysis to identify variants within genomic data sets, and variant effect prediction algorithms (desired)
- Experience with use of Perl, Python, or other programming language (desired)
- Ability to create scripts and process large quantities of data (desired)
QUALIFICATIONS:
- Clinical Genomic Scientist I
- Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master's degree and appropriate experience will be considered.
- Relevant experience: 0-2 years
- Certification (optional): MB(ASCP)
- Clinical Genomic Scientist II
- Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master's degree and appropriate experience will be considered.
- The Clinical Genomic Scientist II demonstrates a strong understanding of the principles of variant curation and genetic data analysis.
- Relevant experience: 2-4 years
- Certification (optional): MB(ASCP)
- Clinical Genomic Scientist III
- Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject. Strong candidates with a Master's degree and appropriate experience will be considered.
- The Clinical Genomic Scientist III demonstrates a consistent high level of performance and leadership abilities.
- Relevant experience: 4-7 years
- Certification (optional): MB(ASCP)
- Senior Clinical Genomic Scientist
- Degree: PhD or MD level degree in clinical medicine, genetics, molecular biology, or an equivalent subject.
- The Senior Clinical Genomic Scientist demonstrates initiative, innovation, and process improvement abilities.
- Relevant experience: 7+ years
- Certification (optional): MB(ASCP)
PHYSICAL DEMANDS AND WORK ENVIRONMENT
- Location: Onsite / Hybrid / Remote
- Frequently required to sit or stand
- Frequently required to utilize hand and finger dexterity to operate keyboard
- Frequently required to attend virtual meetings, listen, and talk
- Occasionally required to work additional hours to complete tasks, with compensatory time-off provided
- Special conditions (e.g. lab/clinical requirements if applicable)
