OverviewHOURLY RATE (DEPENDING ON SKILLS/EXPERIENCE): $65.00 - $89.00SCOPE: The Infusion Nurse - Cellular Therapy and Clinical Research (full-time) is responsible for the safe and compliant administration of investigational and commercial therapies, including cellular therapies (e.g., CAR-T), within an outpatient oncology setting. This role supports both clinical care and research operations, ensuring adherence to protocol requirements, regulatory standards, and institutional policies. The position may require occasional weekend coverage (see schedule notes).
Responsibilities KEY RESPONSIBILITIES:Clinical Care and Infusion Services- Administer oncology therapies, including chemotherapy, immunotherapy, and cellular therapies, in accordance with established protocols and manufacturer guidelines
- Perform pre-infusion assessments, including review of labs, orders, and patient eligibility
- Perform venipuncture/blood draws for clinical and research purposes (routine labs, PKs, and study samples)
- Monitor patients during and post-infusion, including management of adverse events such as cytokine release syndrome (CRS) and neurotoxicity (ICANS)
- Ensure emergency preparedness, including appropriate escalation and coordination with higher levels of care as needed
- Maintain chain of identity and chain of custody for cellular therapy products
Cellular Therapy (CAR-T) Program Support- Participate in cellular therapy workflows, including product receipt, handling, verification, and bedside coordination
- Support cryopreserved product handling, including thawing procedures in accordance with SOPs
- Coordinate with apheresis centers, manufacturers, and couriers as needed
- Ensure compliance with manufacturer requirements and applicable regulatory standards
- Ensure site preparedness for CAR-T, including but not limited to readiness of clinical personnel involved in patient care and SOPs
- Responsible for end to end patient coordination and care for patients undergoing CAR-T - ensuring all steps occur safely
- Participate in weekend coverage to support CAR-T patient monitoring during high-risk post-infusion periods (e.g., CRS and neurotoxicity monitoring windows). Weekend coverage typically runs 8:00 AM-12:00 PM and is scheduled as needed when a CAR-T patient requires monitoring (not every weekend).
Clinical Research Support- Execute study-related procedures per protocol, including sample collection, processing, and documentation
- Collaborate with clinical research staff to ensure protocol adherence and accurate data capture
- Support sponsor monitoring visits and audits as applicable
- Maintain source documentation in accordance with GCP and institutional standards
- Responsible for end to end patient coordination and care for patients enrolled in a clinical trial - ensuring all steps occur safely
Schedule Notes- Full-time position (standard shift 8:00 AM-5:00 PM). There will be occasions when the 8:00 AM-5:00 PM day may extend beyond scheduled hours to accommodate specific clinical or study-related lab draws (e.g., PK sampling) or other time-sensitive patient care needs.
- Occasional weekend obligations (8:00 AM-12:00 PM) as needed to cover CAR-T patient monitoring; these are not every weekend but occur based on patient clinical needs and program scheduling.
- Participate in meetings related to cellular therapy or clinical trial
Compliance and Documentation- Document all clinical and research activities accurately within the electronic medical record and study systems
- Adhere to SOPs, regulatory requirements, and quality management processes
- Participate in training, competency assessments, and quality improvement initiatives
Collaboration and Communication- Work closely with physicians, research staff, pharmacy, and external partners to ensure coordinated patient care
- Communicate effectively regarding patient status, protocol requirements, and operational workflows
Qualifications Qualifications:- Active Registered Nurse (RN) license in the state of California
- Bachelor of Science in Nursing (BSN) preferred
- Minimum 2-3 years of oncology infusion experience required
- Experience with clinical trials and/or cellular therapy preferred
Preferred Qualifications:- Experience with CAR-T or stem cell transplant programs
- Familiarity with GCP, FDA regulations, and clinical research processes
- Experience managing oncology-related toxicities and infusion reactions
Key Competencies:- Strong clinical judgment and critical thinking
- Attention to detail and regulatory compliance
- Ability to operate in a fast-paced, multidisciplinary environment
- Excellent communication and organizational skills
WORK ENVIRONMENT: The conditions described below reflect the typical environment encountered while performing the essential duties of this role. Reasonable accommodation may be provided to support individuals with disabilities in fulfilling these responsibilities. This position operates within a climate-controlled medical office setting. It involves working under pressure and regularly interacting with a diverse group of individuals, including staff, physicians, patients, clients, insurance representatives, and the general public. The role may involve frequent exposure to clinical hazards such as communicable diseases, bodily fluids, hazardous substances, ionizing radiation, and various medications typically present in a healthcare environment.
PHYSICAL DEMANDS: The physical requirements outlined below represent those necessary for an employee to perform the essential duties of this role successfully. Reasonable accommodation may be made to support individuals with disabilities. This position requires a full range of physical movement, including lifting and assisting patients, as well as manual dexterity and coordination. Prolonged periods of standing and walking are expected. The role may occasionally involve lifting and carrying items weighing between 11 and 20 pounds. Adequate vision and hearing, with or without correction, are necessary for effective performance.
Note: This job description provides a general overview and is not intended to detail every responsibility. Additional duties may be assigned as needed to support organizational objectives.
