Cardiometabolic Research at Eli Lilly and Company advances preclinical research aimed at understanding and treating obesity and related metabolic diseases.
We are seeking a skilled, motivated, and versatile individual who can help to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The successful candidate will use a strong in vivo pharmacology background and complementary wet laboratory experience to play a critical role in supporting end-to-end discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. The candidate will be responsible for setting up critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.
Responsibilities:The Research Associate will perform and support in vivo pharmacology studies in rodent models, working under the direction of project scientists. In this role, you will implement study procedures with precision, collect and process biological samples, and document results accurately so that they can be analyzed and shared with the broader research team. The responsibilities include, but are not limited to, the following:
- Perform rodent handling, blood collection, and dosing by subcutaneous (SC), oral (PO), and intraperitoneal (IP) routes according to study protocols.
- Measure and record body weight, body composition, and food intake throughout the course of in vivo studies.
- Collect tissues at study termination and complete downstream sample processing for analysis.
- Perform molecular and biochemical assessments (qPCR, Western blot, ELISA, etc).
- Function independently, work within a team-oriented lab environment, and work within cross-functional project teams.
- Analyze data independently, keep accurate records, and report data in written and oral formats. Perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.
Basic Requirements:B.S. and/or M.S. in biology or a related scientific field with 2+ years of laboratory experience including hands-on in vivo rodent research experience
Additional Skills/Preferences:- Demonstrated proficiency in rodent handling and dosing, tissue collection, and downstream sample processing
- Previous experience with metabolic disease models
- Prior work with jugular vein cannulation and continuous infusion models
- Familiarity with pharmacokinetic/pharmacodynamic (PK/PD) concepts
- Experience with tissue culture of adipose, liver, or muscle cells
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$72,000 - $189,200
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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