BA/BS in Pharmaceutical Sciences, Organic/Biochemistry, Chemical/Biochemical Engineering, Biology, or related field with 2 years of experience, or MS with 1 year of experience.
Experience in preparation of buffers and lab reagents.
Familiarity with biological characterization techniques like pH, Nanodrop, and biochemical assays.
Proficient in analytical software such as Excel for data management and analysis.
Strong attention to detail with excellent pipetting and sample preparation skills.
Demonstrated ability to collaborate in cross-functional teams on multiple projects.
Excellent written and verbal communication skills.
Responsibilities
Conduct pre-formulation and formulation studies, including bio-characterization and stability studies.
Run assays for protein concentration, pH, and visual assessments to support team testing.
Assist senior scientists in developing analytical methods for large molecules using techniques like DSC and SEC.
Support process development for various ongoing research projects.
Maintain accurate written records of experiments using Vaxcyte's ELN system.
Collaborate effectively with Analytical and other research teams within the department.
Demonstrate agility in thought processes and practical execution while being scientifically proactive.
Benefits
Comprehensive benefits package including health, dental, and vision insurance.
Equity component as part of the compensation package.
Opportunities for professional development and growth within the company.
Full Job Description
Summary:
Vaxcyte is looking for an energetic and talented individual to play a key supporting role in the Research Department. The successful candidate will be proficient in basic laboratory techniques and be responsible for the support of the senior scientists in the execution of large and complex experimentation. These experiments will primarily take the form of pre-formulation and formulation studies for novel vaccine candidates, stability studies designed to select optimum formulation for tech transfer, process development studies to support projects within research department and troubleshooting studies to remove roadblocks for early-stage pipeline projects. Essential Functions:
Conducting and coordinating pre-formulation and formulation studies, including bio-characterization studies, excipient screening, short- and long-term stability studies.
Responsible for testing support for within the team which includes running assays such as protein concentration, pH and visual assessments.
Support senior scientists in developing analytical methods for biocharacterization of large molecules such as DSC, CD, SEC and other similar techniques.
Support senior scientists in developing processes to support a wide range of ongoing research projects.
Being scientifically accurate and keeping excellent written records of experiments undertaken using Vaxcyte's ELN system.
This position will report into the Formulation and Process line within the Research Department. Significant partnerships with the Analytical and other research teams will occur, thus ability to work within this collaborative environment is essential.
This role will require the incumbent to be agile in both thought processes and practical execution. In addition, being scientifically pro-active within the small group will be encouraged.
Requirements:
BA/BS in Pharmaceutical Sciences, Organic/Biochemistry, Chemical/Biochemical Engineering, Biology, or a related discipline, with a minimum of 2 years of industrial experience; or MS in one of these disciplines with a minimum of 1 year of industrial experience.
Experience in preparation of buffers and lab reagents required.
Experience in basic biological characterization techniques preferred, including pH, Nanodrop, biochemical assays and particle size determinations
Highly efficient and structured work practices including practical laboratory work, notebook upkeep, data generation and presentation to research and wider teams.
Experience with analytical software like Excel for data entry/maintenance and analysis. An understanding of analytical statistical analysis is also preferred.
Attention to detail and excellent skills in pipetting and sample preparation
Demonstrated ability to work collaboratively in a cross-functional team environment on multiple projects
Strong interpersonal skills, with excellent written and verbal communication skills
Reports to: Staff Scientist, Research
Location: San Carlos, CA
Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy):
Onsite (minimum of 4 days per week onsite)
Compensation:
The compensation package will be competitive and includes comprehensive benefits and an equity component.
Salary Range: $108,000 - $120,000
About Vaxcyte
Vaxcyte is a clinical-stage biotechnology company developing a new generation of vaccines to address some of the most important and deadly infectious diseases worldwide. The company's cell-free protein synthesis platform, comprising the XpressCFTM platform, is capable of rapidly generating protein antigens that can be used in vaccines to protect against bacterial and viral pathogens. Vaxcyte's lead vaccine candidate, VAX-24, is a preclinical, 24-valent pneumococcal conjugate vaccine (PCV) being developed for the prevention of pneumococcal disease. The company is also developing VAX-XP, a PCV with expanded serotype coverage, as well as vaccines for Group A Streptococcus, Group B Streptococcus, and Lyme disease.
