Extensive experience with mouse models and stereotaxic injections
Strong background in molecular and cell biology
Proficiency in laboratory techniques such as cell culture and Western blotting
Demonstrated self-motivation and scientific rigor
Ability to work independently at the bench
Responsibilities
Perform in vivo experiments using mouse models, including stereotaxic injections
Conduct molecular and cell biology experiments to support research projects
Execute laboratory techniques like DNA/RNA isolation and immunohistochemical labeling
Develop methodologies and analyze data for medical applications
Design and conduct complex research studies evaluating various experimental approaches
Collaborate with healthcare professionals and researchers to support initiatives
Provide training on laboratory procedures to staff and students
Benefits
Access to cutting-edge research facilities
Opportunity to work with leading experts in neurobiology
Engagement in impactful research on Alzheimer's disease
Collaborative environment fostering innovation
Potential for professional development and training opportunities
Full Job Description
Job Description
The Pereira Laboratory at the Icahn School of Medicine investigates the neurobiology of Alzheimer's disease, including the selective regional and cellular vulnerability to tau pathology and neurodegeneration. We are seeking an outstanding Associate Scientist to join the lab's efforts to discover and validate novel therapeutic targets using animal models, postmortem human tissue, iPSCs, and bioinformatics.
Responsibilities
Perform in vivo experiments using mouse models, including stereotaxic injections.
Conduct molecular and cell biology experiments to support ongoing research projects.
Perform laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
Conduct research to develop methodologies, instrumentation, and procedures for medical applications, including analyzing data and presenting findings.
Design and conduct complex research studies, evaluating alternative methods, computational models, and experimental approaches.
Plan and conduct studies investigating human or animal diseases, preventive methods, and potential treatments.
Assist in clinical laboratory operations, as needed.
Follow established laboratory safety procedures to prevent contamination and ensure compliance with safety standards.
Provide training and guidance on medical and laboratory procedures to physicians, residents, students, and research staff.
Collaborate with healthcare professionals, researchers, and other stakeholders to support research initiatives and health safety standards.
Develop research tools, techniques, and methodologies to support scientific investigations.
Identify research questions, develop hypotheses, and establish methodologies for evaluating experimental results.
Analyze and interpret research findings and communicate results through scientific publications and presentations.
Develop research proposals and seek support for new and ongoing research activities.
Provide scientific recommendations to support research activities and project objectives.
Perform other related duties.
Qualifications
Ph.D. in Biological Science or related field
Three years' experience
Highly Preferred Experience:
Extensive experience working with mouse models, including performing stereotaxic injections.
Strong background in molecular and cell biology.
Experience with laboratory techniques, including cell culture, DNA/RNA isolation, cellular fractionation, Western blotting, PCR/qRT-PCR, in situ hybridization, and immunohistochemical labeling.
Strong interest in neurodegeneration highly preferred.
Demonstrated self-motivation, enthusiasm, and scientific rigor.
Ability to work independently at the bench.
About Mount Sinai Hospital
Mount Sinai Hospital is a hospital network based in New York City. It was founded in 1852 and is one of the oldest and largest teaching hospitals in the United States. The hospital has been ranked among the top hospitals in the country by U.S. News & World Report and is known for its excellence in patient care, research, and education. Mount Sinai Hospital is affiliated with the Icahn School of Medicine at Mount Sinai and has a staff of over 7,000 physicians, nurses, and other healthcare professionals.
