Job DescriptionRole Overview:Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking a talented and motivated candidate to join the R&D cell biology and immunology lab at US site. The successful candidatewill contribute to the company's efforts to develop next-generation cell therapies in solid tumor malignancies. The successful candidate will have a strong Molecular biology/Cell biology and Immunology background, and expect to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.
Major Responsibilities: - Assist in developing T cell therapy platform, perform cell-based immunoassays, including ex-vivio antigen specific T cell isolation and expansion, Viral-vector based introduction ofTCRs / CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays
- Culture and characterize genetically modified human T cells and tumor cells including gene expression and cell functionalities testing
- Plan and execute in vitro functional assays with T cells according to project goals and timelines.
- Effectively communicate plans and results in both oral and written form.
- Ability to work in a highly dynamic collaborative team environment.
- Other duties as assigned
QualificationsEducation:- B.S or M.S. in biomedical science field or cell biology and immunology
Experience: - > 5 year with B.S. or 2-5 year with M.S. Industry/academic experience inImmunology/Cell Biology, preferably Immunotherapy.
Key Capabilities, Knowledge, and Skills: - Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required.
- Experience with primary T cell-based assays preferred.
- Excellent mammalian cell/tissue culture and sterile technique required.
- Strong organizational skills and record keeping.
- Self-motivated and willing to accept temporary responsibilities outside of initial job description.
- Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
- Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment.
