Posting Details
Position Details
Title
Assistant Scientist - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model
Appointment Status
Non-Tenure Track
Department
IU Bloomington Intelligent Systems Engineering
Location
Bloomington
Position Summary
AI-Enabled Immune Digital Twin & Organ damage Mechanistic Model Scientist: Assistant Scientist; Biocomplexity Institute at Indiana University Bloomington (PI: Dr. James A. Glazier)
Your primary duties will be to develop biologically meaningful, interpretable model components linking immune-state dynamics to organ-damage risk (lung, kidney, liver) in critical illness under the direction of Dr. James A. Glazier. You will map clinical biomarkers to model states, define biological scoring criteria for digital twin ensembles, collaborate with national consortium partners, write technical publications, and prepare milestone-ready contract deliverables.
60% Dynamic Immune & Organ Modeling: Develop fast, interpretable
ODE/network/mechanistic model modules linking immune dysfunction to organ injury; map clinical time-series and biomarkers to model states; formulate biological plausibility and scoring criteria.
40% Consortium Deliverables & Research: Prepare test cases, model packages, and model cards; write research papers; present findings; collaborate with national consortium partners in systems biology and clinical data science.
Basic Qualifications
Ph.D. or equivalent terminal degree in quantitative, computational, or biomedical discipline.
Programming proficiency in Python, Julia, R, or MATLAB; background in mechanistic modeling (ODE/dynamical systems, QSP, or agent-based); familiarity with inflammation, cytokine signaling, sepsis, or critical care biology.
One year of successful postdoctoral research experience.
Department Contact for Questions
Please contact Professor James Glazier at glazier@iu.edu.
Additional Qualifications
Salary and Rank
100,000/Assistant Scientist
Special Instructions
For Best Consideration Date
11/02/2026
Expected Start Date
Posting Number
IU-101731-2026
