We are looking for an Applied Scientist III to set the scientific direction for the next generation of agentic AI applications that guide Amazon advertisers. In this role you will define, lead and build the science behind agentic systems that reason, plan, and act autonomously to manage and optimize ad campaigns based on a deep understanding of the advertiser and the marketplace. You will own the agentic architecture end to end, partnering closely with product and engineering leaders to translate a long-term science vision into concrete research and engineering roadmaps. Working backwards from the needs of millions of advertisers, you will take the lead on medium-to-large, ambiguous problems where neither the problem nor the solution is well defined, and deliver customer-facing products that help advertisers create, optimize, and grow their campaigns. You will invent new methods at the product level, and drive their adoption across multiple teams. This role combines science leadership, technical depth, product focus, and business understanding: you will raise the science bar, build consensus on approach across partners, and mentor scientists and engineers while remaining deeply hands-on with the hardest technical problems. Key job responsibilities As an Applied Scientist III on this team you will: - Define the science vision for the agentic campaign management system and, with product and engineering leaders, turn it into delivery roadmaps. - Build agentic systems that autonomously manage and optimize ad campaigns - encoding auction and marketplace dynamics (bidding, budget pacing, keyword and targeting decisions) while balancing advertiser ROI, shopper experience, and marketplace health. - Define and curate the datasets and signals needed to train and evaluate these agents - advertiser and campaign data, auction and bid/budget signals, impressions, clicks, conversions, and search-term/keyword performance. - Stay deeply hands-on: write production-quality, critical-path code and build core components that take agentic systems from prototype to launch. - Own the agentic architecture - planning, tool use and integration (e.g., MCP), long-horizon reasoning (e.g., ReAct, CoT/ToT), and multi-agent orchestration - and stay deeply hands-on, writing production-quality, critical-path code from prototype to launch. - Define the evaluation and safety methodology for agent workflows and drive its adoption as the bar for reliability and trust. - Drive the team's scientific agenda, mentor scientists and engineers, and represent the team in the internal and external scientific community. BASIC QUALIFICATIONS - 5+ years of building machine learning models for business application experience - PhD, or Master's degree and 6+ years of applied research experience - Experience programming in Java, C++, Python or related language - Experience with neural deep learning methods and machine learning PREFERRED QUALIFICATIONS - Experience with modeling tools such as R, scikit-learn, Spark MLLib, MxNet, Tensorflow, numpy, scipy etc. - Experience with large scale distributed systems such as Hadoop, Spark etc. - Experience building high-velocity ad products - Experience developing, deploying and managing AI products at scale The base salary range for this position is listed below. Your Amazon package will include sign-on payments and restricted stock units (RSUs). Final compensation will be determined based on factors including experience, qualifications, and location. Amazon also offers comprehensive benefits including health insurance (medical, dental, vision, prescription, Basic Life & AD&D insurance and option for Supplemental life plans, EAP, Mental Health Support, Medical Advice Line, Flexible Spending Accounts, Adoption and Surrogacy Reimbursement coverage), 401(k) matching, paid time off, and parental leave. Learn more about our benefits at https://amazon.jobs/en/benefits. USA, CA, Palo Alto - 192,200.00 - 260,000.00 USD annually USA, NY, New York - 183,800.00 - 248,700.00 USD annually USA, WA, SEATTLE - 167,100.00 - 226,100.00 USD annually