Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$81K - $100K *
Deliver exceptional client service by managing strategic accounts, driving retention, and fostering growth. Collaborate with cross-functional teams to address customer needs and expand business opport...
2 weeks ago
Senior Sales Strategy & Operations Manager
$136K - $171K *
Drive strategic sales operations initiatives to enhance efficiency, optimize processes, and support predictable growth, enabling a global sales organization to thrive in a dynamic, data-driven environ...
3 weeks ago
$178K - $245K *
Drive end-to-end digital transformation for enterprise supply chains, managing high-stake programs while leading cross-functional teams. Ensure delivery excellence, foster client relationships, and op...
3 weeks ago
$160K - $220K *
Transform commercial contracting by leading negotiations and enhancing workflows. Collaborate with cross-functional teams to drive compliance and strategic outcomes, ensuring legal support scales effe...
2 weeks ago
$125K - $150K *
Engage in strategic finance management by leading financial modeling, budgeting, and analysis processes. Collaborate with leadership to drive data-driven decisions and enhance financial infrastructure...
1 month ago
Senior Enterprise Account Executive
$125K - $150K *
Grow your career with a leading payroll solution provider, driving enterprise sales and developing client relationships in large organizations while managing complex sales cycles and achieving signifi...
Reposted 2 weeks ago
$70K - $140K *
Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...
Reposted 2 weeks ago
$110K - $130K *
Transform the mobile product experience by leading design initiatives that empower creators and engage fans. Drive product quality and innovation through hands-on design, collaboration, and strategic...
2 weeks ago
Enterprise Client Relationship Executive
$105K - $130K *
Join a team that's dedicated to transforming the future of healthcare finance. Collaborate with cross-functional teams to enhance service delivery and drive innovative solutions that empower clients a...
3 days ago
$224K - $282K *
Lead the charge in transforming new business sales, driving revenue growth, and shaping go-to-market strategies while managing a high-performing team and collaborating across departments to enhance cu...
2 weeks ago
Corporate Finance Manager, Fundraising and Investor Relations
$133K - $166K *
Champion the fundraising efforts of a dynamic corporate finance team, managing complex debt and equity processes while collaborating with senior leadership to craft compelling narratives for investors...
1 week ago
$110K - $130K *
Engage your expertise to lead bridge and structural projects from planning to completion. Manage multidisciplinary teams, maintain client relationships, and drive practice growth across Massachusetts...
5 days ago
$95K - $115K *
Champion the successful delivery of customer projects through all phases, ensuring alignment with business goals by coordinating teams and resources while managing risks and transacting key communicat...
3 weeks ago
Senior Technical Account Manager
$110K - $130K *
Contribute to customer success as a technical liaison, driving adoption of AI-driven solutions while collaborating with cross-functional teams to enhance product value and performance. Foster strong r...
Reposted 2 weeks ago
Director, Business Development
$150K - $180K *
Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...
Reposted 3 weeks ago
Key Account Manager - Dallas, TX
$170K - $205K *
Transform sales strategies by driving key account growth, building relationships, and executing plans for a new kidney transplant product. Collaborate cross-functionally to ensure optimal market acces...
2 weeks ago
VP, Relationship Manager - Industrial
$125K - $150K *
Advance your career by driving strategic vendor finance relationships in the industrial equipment sector. Lead business development efforts, manage key partnerships, and deliver tailored financing sol...
4 days ago
Senior Partner Sales Executive - Strategic Commercial
$222K - $360K *
Drive growth by developing and executing strategic partnerships with large enterprises. Leverage your expertise to enhance relationships, optimize offerings, and lead cross-functional collaboration fo...
2 weeks ago
$138K - $165K *
Elevate our product management efforts by driving innovation in cybersecurity. Collaborate with cross-functional teams to deliver impactful data-driven analytics, leveraging user insights and industry...
Reposted 1 week ago
$80K - $95K *
Empower our analyst relations program by managing evaluations, timelines, and coordination. Collaborate with stakeholders to ensure accurate, timely engagement and support market insights for strategi...
Reposted 3 weeks ago
Director, Sourcing & Procurement
$190K - $237K *
Optimize sourcing strategies and procurement processes for clinical operations, ensuring effective vendor management and governance across global clinical trials. Collaborate with cross-functional tea...
1 week ago
Head of Business Development, IDD & Behavioral Health
$200K - $270K *
Accelerate progress at multi-state market development by building key relationships, navigating complex contracting processes, and driving approvals in Medicaid and managed care environments. Own the...
1 week ago
Enterprise Account Executive, Observability
$150K - $180K *
Drive success by leveraging your expertise in enterprise sales to enhance customer engagement and expand market presence. Collaborate cross-functionally to deliver innovative solutions that empower or...
1 week ago
$80K - $95K *
Accelerate progress at the forefront of scientific sales by driving growth across diverse markets. Leverage your expertise to build relationships and solve complex challenges while managing the full s...
2 days ago
$163K - $224K *
Join a team that's redefining People Operations by leading global service delivery, enhancing employee experiences, and driving operational excellence across Talent Acquisition and People processes fo...
Reposted 1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.