Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$146K - $215K *

Elevate your career by leading supplier development initiatives, enhancing manufacturing capabilities, and driving operational excellence. Collaborate cross-functionally to ensure supplier readiness a...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Shape the people operations landscape by enhancing core processes and supporting the employee lifecycle. Collaborate with leadership to ensure compliance and scalability as the company rapidly grows i...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Unlock potential by transforming revenue data into actionable insights. Collaborate closely with GTM teams to enhance decision-making processes through robust dashboards, analyses, and thorough report...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $105K *

Partner with us to enhance organizational effectiveness by guiding leaders and employees in talent management, engagement, and performance strategies, fostering a high-performing culture and exception...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Champion a data-driven demand generation strategy by managing our entire digital marketing ecosystem. Drive qualified pipeline growth across diverse sectors through hands-on execution in automation, S...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Unlock potential by driving transformational sales initiatives and cultivating strategic partnerships. Engage with C-suite stakeholders to shape enterprise revenue and influence market direction throu...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$100K - $115K *

Join a team that's dedicated to ensuring compliance and employee relations excellence. Oversee workforce compliance frameworks, streamline processes, and partner with HR and operations to enhance safe...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $231K *

Lead the charge in product execution, driving growth and market penetration by collaborating with sales teams to develop strategies and equip them with tools for success. Enhance customer value throug...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$73K - $100K *

Take ownership of evaluating and enhancing internal financial controls, ensuring compliance and effectiveness across processes and systems. Collaborate cross-functionally to identify risks and impleme...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the full sales cycle by engaging with enterprise clients, driving revenue growth, and enhancing customer relationships in the construction industry. Leverage your expertise to meet and exceed...

US-AnywhereRemote

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$167K - $199K *

Shape the future of power electronics by creating customer-centric designs, optimizing systems, and engaging with diverse teams to innovate products and solutions that meet market demands and technica...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$105K - $165K *

Champion the defense of complex medical malpractice and liability claims. Manage litigation strategies, collaborate with executive leadership, and ensure comprehensive oversight from investigation to...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$131K - $180K *

Shape the future of internal communications by partnering with business units to develop and execute strategies that engage and inform global audiences, ensuring alignment with organizational goals an...

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$207K - $331K *

Transform clinical radiation therapy by leveraging advanced physics expertise to optimize complex treatment planning, improve safety protocols, and enhance patient experiences across multiple faciliti...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$207K - $331K *

Deliver advanced medical physics expertise in radiation oncology across Northern Area clinics, collaborating with a multidisciplinary team to improve patient outcomes through innovative treatment plan...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$106K - $132K *

Drive local market execution and performance by collaborating with teams, leveraging data for growth, and managing distributor relationships to ensure alignment with strategic goals and operational ex...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$320K - $405K *

Unlock your potential by driving large-scale compute capacity deployments in partner-operated data centers. Manage hardware installations, collaborate with vendors, and optimize processes while ensuri...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$65K - $108K *

Play a key role in ensuring coding accuracy and compliance by reviewing medical records across various specialties. Leverage your expertise to enhance quality and efficiency in coding practices...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$83K - $138K *

Transform global revenue assurance by leading accurate, compliant revenue processes. Collaborate with cross-functional teams to analyze complex contracts, drive improvements, and enhance scalability a...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$162K - $219K *

Empower strategic growth by leading partnerships in AI, hardware, and SaaS ecosystems. Manage the entire partnership lifecycle, drive measurable results, and collaborate with cross-functional teams fo...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$106K - $151K *

Grow your career with a dynamic team focused on delivering IoT solutions to small and medium businesses. Engage in end-to-end customer engagements, driving impactful sensor data insights while managin...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$178K - $319K *

Explore the potential of AI/ML to revolutionize supply chain efficiency. Collaborate across departments to optimize logistics and inventory management. Drive impactful solutions using cutting-edge mod...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$143K - $273K *

Shape the future of HR by leading strategic enablement initiatives that drive effective adoption and execution of HR programs across the organization, ensuring alignment with business outcomes and enh...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$121K - $170K *

Drive your career forward as a strategic leader, guiding enterprise-level technology solutions. Engage with executive stakeholders, architect innovative multi-practice solutions, and influence digital...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.