Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$80K - $105K *

Join a supportive team and provide exceptional therapy services to children and adults. Engage in a fulfilling, clinic-based role focused on enhancing the well-being of patients, with flexibility for...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of enterprise advertising by driving growth across a strategic portfolio. Engage with executive clients, reactivation of dormant accounts, and foster collaboration, leveraging your ex...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Join a team that's transforming customer relationships by driving growth, fostering strong partnerships, and delivering tailored solutions. Be a key contributor in maximizing retention and exploring n...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Innovate your career by leading SAP S/4HANA transformations, guiding clients through Order to Cash solutions, and enhancing operational efficiency while establishing strong partnerships and delivering...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$111K - $137K *

Shape the future of workplace culture and safety by partnering with leadership to enhance employee engagement, drive organizational change, and ensure compliance with safety regulations in a dynamic m...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $115K *

Champion the growth of key accounts by driving sales performance, building partnerships, and executing strategic initiatives. Utilize market insights to identify opportunities and enhance business eff...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Shape the future of sales by owning the entire sales cycle, driving growth through outbound prospecting, and collaborating with stakeholders to close impactful deals in the innovative SaaS sector...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the compliance and documentation efforts, ensuring robust privacy and security practices. Collaborate across teams to create and maintain essential documentation, audits, and operational workflow...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $160K *

Optimize HR technology strategies and systems by leading functional ownership of the HRIS ecosystem. Oversee data integrations and partner across teams to ensure reliable, scalable, and efficient HR o...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $110K *

Empower network performance by supporting enterprise infrastructure, troubleshooting connectivity issues, and collaborating with cross-functional teams to enhance security and reliability in a hybrid...

Today

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Empower the implementation and optimization of Oracle Fusion Cloud HCM applications, managing all aspects of Core HR, Time & Labor, and Absence Management. Collaborate across departments to ensure eff...

1 month ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Drive your career by building relationships with senior healthcare leaders, managing a robust sales pipeline, and delivering impactful Smart Room solution presentations to achieve sales goals and enha...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$167K - $234K *

Develop and execute comprehensive strategies for advertiser fraud detection, leveraging cross-functional partnership to create robust playbooks and scalable automated defenses against sophisticated th...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Media

$172K - $202K *

Lead supply chain strategy development by analyzing trends. Collaborate with CSCOs, providing insights and thought leadership through research and presentations. Drive implementation of best practices...

US-AnywhereRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$100K - $120K *

Elevate executive effectiveness by providing proactive support to leadership. Manage complex schedules, coordinate meetings, and drive strategic initiatives while enhancing employee engagement and wor...

6 days ago

  •   5 - 7 years exp.  •   Transportation

$243K - $286K *

Elevate customer experiences by leading a dynamic product team focused on AI-driven support solutions. Drive strategy and innovation to enhance engagement for over 100 million users while balancing au...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$89K - $111K *

Elevate your career as a senior individual contributor, driving tech integration partnerships. Manage complex deals from negotiation to go-live with a dedicated engineering team, influencing how solut...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $118K *

Empower patient care through comprehensive nursing practices. Deliver excellence in dynamic clinical environments while collaborating with multidisciplinary teams to ensure safety and quality care out...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Transform patient care delivery by collaborating across teams to enhance safety and quality in nursing practices. Utilize a dynamic skill set to assess, implement, and evaluate care, optimizing patien...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$146K - $198K *

Join a team that's driving growth by engaging new customers and expanding product success. As a key player in the sales cycle, you'll navigate opportunities, refine strategies, and contribute tangible...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$128K - $160K *

Drive your career forward by leading new logo acquisition with AI/ML teams. Own the sales cycle, build consensus across stakeholders, and deliver accurate forecasting while connecting AI products to g...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $152K *

Lead the charge in architecting and modernizing enterprise workload automation systems, driving strategic initiatives and cross-functional collaboration to enhance efficiency and integrate AI capabili...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Join us to empower senior leaders by managing complex projects, client contracts, and travel arrangements. Your proactive support will enhance team efficiency in a fully virtual environment, fostering...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Shape strategic account growth in healthcare with innovative solutions. Collaborate across teams to foster relationships and drive success for a portfolio of existing clients, navigating complex sales...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Champion strategic relationships in the healthcare sector, driving sales growth by identifying opportunities and engaging healthcare executives. Leverage expertise to deliver tailored solutions that a...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.