Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Account Director Jobs in South Dakota

Sort By: Relevance

$184K - $287K *

Empower our channel sales strategy by building and scaling MSP partnerships, driving recurring revenue, and collaborating cross-functionally to establish a robust partner ecosystem that thrives in the...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$99K - $132K *

Advance your career as a Senior Financial Analyst in Treasury, focusing on cash management, corporate finance, and cross-functional collaboration. Drive impactful financial strategies while enhancing...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Media

$131K - $182K *

Empower revenue teams by leading a dynamic group of Revenue Enablement Managers. Drive ongoing performance through strategic coaching, hands-on training, and AI-first initiatives, ensuring alignment a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$213K - $445K *

Advance strategic initiatives in Food & Beverage investment banking by cultivating senior-level relationships, executing complex transactions, and providing expert advisory services to clients, drivin...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$113K - $181K *

Discover transformative opportunities by leading advanced analytics capabilities that drive performance and innovation in healthcare. Collaborate with cross-functional teams to create impactful data s...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Unlock your potential as a technical leader driving enterprise identity and messaging services. Manage a talented team of engineers, ensuring reliable operations and security in a hybrid environment w...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$130K - $219K *

Transform the monetization landscape by leading product strategies that drive market success. Collaborate across diverse product lines to enhance pricing models and optimize profitability, ensuring im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Champion strategic HR initiatives by partnering with Finance and Legal teams to enhance talent management, organizational design, and employee engagement, driving impactful people strategies that alig...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Explore a leadership role driving expansion revenue by coaching Account Managers, identifying growth opportunities, and enhancing strategies within Mega and Large real estate teams to achieve signific...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $180K *

Lead the charge in forging transformative partnerships within the entertainment industry, crafting AI-driven demonstrations to showcase innovative filmmaking technologies and fostering long-term colla...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Media

$149K - $248K *

Lead the transformation of Workday Financial Management, ensuring effective design and implementation across finance and enterprise processes. Collaborate with cross-functional teams to optimize ERP c...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$90K - $125K *

Transform complex commercial casualty claims management by leveraging your expertise in construction-related exposures and litigation. Collaborate with a dedicated team to deliver exceptional outcomes...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$116K - $159K *

Drive growth through data-driven strategies by analyzing user signals, optimizing marketing pathways, and collaborating cross-functionally to enhance our digital presence. Shape compelling activation...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $100K *

Transform software delivery by managing cross-functional teams, aligning sprints, and optimizing project timelines. Drive clarity in processes and foster collaboration to ensure successful product exe...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by managing strategic partnerships to enhance capabilities, drive client opportunities, and foster collaboration across teams. This role requires a proactive approach to relationship...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$185K - $315K *

Join a team that's shaping global tax strategy and compliance. In this leadership role, you'll drive tax planning, manage risks, and collaborate with executives to support business growth in a dynamic...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$90K - $100K *

Unlock your potential by driving sales of retirement plans in a dynamic market. Build relationships with financial intermediaries and plan sponsors while managing a targeted territory to achieve ambit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Drive your career with a pivotal role in Medical Informatics sales, focusing on building relationships, achieving revenue goals, and collaborating across teams to enhance customer experiences and expa...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$114K - $171K *

Join a team that's driving growth in clinical trials by identifying and securing partnerships. Collaborate with cross-functional leaders to enhance visibility and expand opportunities, ensuring seamle...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Empower your career by driving project delivery and managing Agile teams. Utilize AI tools to enhance decision-making, anticipate risks, and ensure timely outcomes. Collaborate with stakeholders to ma...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $195K *

Transform enterprise sales and modernization for retirement technology. Lead a team of Sales Engineers, engaging with diverse stakeholders to deliver tailored solutions and drive impactful customer ex...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive growth by leading a team of provider relations representatives, managing key provider relationships, and implementing strategies to enhance service offerings and revenue within the compounding p...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Explore a vital leadership role in financial planning and analysis, guiding strategic decisions. Partner with senior management to enhance operational efficiency and financial performance, delivering...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$164K - $225K *

Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $180K *

Lead product strategy and outcomes across diverse portfolios, driving team success and aligning customer needs with business objectives. Foster collaboration across functions to deliver impactful prod...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.