Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Client Engagement Director- Preferred candidates Chicago land area / Midwest
$175K - $215K *
Drive strategic growth and client satisfaction by managing senior-level relationships, leveraging cross-functional resources, and delivering measurable business value in a dynamic market environment...
2 weeks ago
$180K - $220K *
Lead the global Accounting and Treasury function, driving financial systems, reporting, and IPO readiness while building a scalable team to support international growth and operational complexity...
Yesterday
$80K - $95K *
Transform your accounting career by managing critical operations for both government contracting and a burgeoning SaaS product line, leading month-end closes, and collaborating across teams to ensure...
3 weeks ago
$95K - $115K *
Empower businesses by analyzing transaction data and crafting actionable insights. Collaborate with sales to design solutions, build prototypes, and present findings to executives, driving enterprise...
3 weeks ago
$170K - $180K *
Transform the sales landscape by leading strategic initiatives that enhance performance management, forecasting, and accountability across the commercial organization, driving profitable growth and ac...
2 weeks ago
$140K - $160K *
Shape the future of demand generation by driving impactful campaigns, collaborating with cross-functional teams, and leveraging AI to enhance marketing efficiency. This role offers a chance to innovat...
3 days ago
Account Executive, Solutions (Upstate NY & New England)
$80K - $95K *
Lead the charge in driving new business and customer success in the education sector. Build trusted relationships with K-12 decision-makers while executing strategic territory plans to achieve sales g...
5 days ago
Global Strategic Partnership Director
$150K - $180K *
Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...
4 days ago
Senior Manager, Business Applications
$120K - $145K *
Elevate your career by leading the strategy and delivery of a robust Salesforce ecosystem, driving business impact through innovative solutions and team development in a dynamic, global environment...
3 weeks ago
Expert Decision Support Analyst
$100K - $120K *
Champion data-driven decision-making by transforming complex marketing insights into actionable recommendations. Collaborate with clients and teams to enhance reporting solutions and drive campaign su...
2 weeks ago
Strategic Account Executive (Chicago & Texas)
$125K - $150K *
Deliver impactful voice AI solutions by driving strategic account growth and managing complex sales cycles. Collaborate across teams to exceed sales targets while fostering relationships with key stak...
Reposted 3 weeks ago
$110K - $130K *
Champion business growth by driving market development in healthcare. Build relationships, achieve sales objectives, and influence cross-functional teams to deliver customer-centric solutions while ma...
6 days ago
$125K - $150K *
Manage financial operations for a large-scale, multi-source IT services program. Collaborate with enterprise partners and ensure accurate financial reporting, chargebacks, and support for invoicing. E...
Reposted 3 weeks ago
Field Operations Director - AMER
$120K - $150K *
Partner with us to build a scalable sales operations framework across the Americas, enhancing forecast accuracy and pipeline management while fostering strong relationships with field leadership and d...
1 week ago
$145K - $175K *
Join a team that's redefining AI-driven solutions by leading product development for an innovative tech concierge. Drive the evolution of agent capabilities, ensuring quality and reliability while col...
6 days ago
$150K - $180K *
Optimize engagement and monetization strategies for an AI-driven product, transforming customer interactions into measurable growth. Lead cross-functional teams to innovate and implement effective use...
6 days ago
Senior Accounting Manager, B2B Revenue
$120K - $145K *
Lead the design and implementation of B2B revenue accounting processes, ensuring efficient contract-to-cash operations while collaborating with cross-functional teams to drive growth and reduce manual...
2 weeks ago
Senior Manager, Monetization- Audiences & Data (REMOTE)
$95K - $158K *
Shape the future of audience data strategy by developing scalable products, enhancing targeting capabilities, and fostering cross-functional collaboration to drive data access and compliance in a dyna...
3 weeks ago
Director, Disease Area Strategy Lead - General Medicine
$195K - $265K *
Lead the strategic direction of General Medicine, integrating scientific and commercial insights to drive portfolio decisions and early pipeline projects, while fostering cross-functional collaboratio...
2 weeks ago
$92K - $138K *
Lead the strategic management of accounts receivable functions, optimizing cash flow and ensuring compliance. Collaborate with teams to enhance efficiency, resolve escalations, and drive performance a...
5 days ago
Lead Product Analyst - Ancillary Products
$94K - $151K *
Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...
1 week ago
Senior Manager, Trust Services
$110K - $130K *
Unlock potential by leading a global team in Trust Services, enhancing client relationships, and driving operational excellence. Shape the future of AI-powered security solutions while ensuring top-ti...
2 days ago
$120K - $140K *
Advance client success by providing technical guidance and support for Ping solutions. Collaborate across teams to ensure seamless implementation and ongoing optimization, fostering strong relationshi...
Reposted 3 weeks ago
Sales Executive, Partnerships & Alliances - MLF
$136K - $253K *
Transform revenue growth by driving sales of partnership products to Mid Law High Value Accounts. Collaborate with territory owners and manage complex sales cycles while leveraging deep product knowle...
2 weeks ago
North America Digital Solutions Key Account Director
$150K - $180K *
Inspire growth by leading strategic initiatives for key telecom accounts, fostering executive relationships, and driving multi-year revenue plans. Collaborate across teams to align solutions with evol...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.