Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$135K - $160K *

Unlock growth by leading sales initiatives and driving new opportunities in Salesforce services. Collaborate with teams to develop strategic solutions, manage client relationships, and exceed revenue...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Develop strategic relationships and drive lubricant sales in New England and New York. Lead account planning, assess distributor needs, and achieve sales targets while collaborating with internal team...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$215K - $289K *

Lead the charge in driving legal strategy and contract negotiations across all business units, ensuring compliance and supporting revenue growth through effective collaboration with sales, finance, an...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Optimize operational excellence and client service as a senior leader overseeing a complex Connected Solutions hub, ensuring high standards in production, technical operations, and team performance fo...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Media

$90K - $110K *

Engage with powersports dealerships to expand financing partnerships, drive sales growth, and enhance dealer relationships. Utilize market insights to develop strategic plans and support dealer onboar...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$228K - $262K *

Grow your career with a strategic role focused on acquiring enterprise clients. Engage with C-level executives, manage complex sales cycles, and drive new business through consultative selling and rel...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$265K - $325K *

Help us shape a dynamic legal environment as you partner with executive teams to enhance compliance, privacy, and contracting processes, contributing to the successful integration of two leading healt...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Engage with new business opportunities to drive growth and market share in the South-Central U.S. Collaborate with teams to launch solutions, manage customer relationships, and achieve sales targets w...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$175K - $210K *

Drive the go-to-market strategy for an AI-powered enterprise search platform, leading a high-performing sales team to achieve revenue goals while fostering strategic partnerships and aligning with pro...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$119K - $140K *

Drive strategic outbound sales efforts to secure new enterprise accounts, leveraging your expertise in solution selling and relationship building with C-suite executives to expand market presence and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$70K - $140K *

Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$500K+*

Join a team that's driving sales success through strategic leadership and collaboration. Oversee resource planning, manage budgets, and coach a team of Regional Sales Managers while achieving revenue...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Join a team that's shaping the future of concrete solutions by driving market growth and expanding business opportunities. Utilize your sales expertise to engage with industry stakeholders and deliver...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$202K - $250K *

Elevate the Personal Care department by driving strategic billing and claims initiatives, optimizing processes for accuracy and compliance, and leading a high-performing team to achieve operational ex...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$160K - $200K *

Advance your career by leading innovative market access strategies across biopharma clients. Collaborate with cross-functional teams to shape access, reimbursement, and patient support, driving impact...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Shape the future of market access strategy by integrating payer, provider, and patient perspectives. Lead cross-functional teams to develop impactful strategies that enhance therapy positioning and su...

Philadelphia, PARemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Lead the charge in optimizing top-of-funnel marketing operations, driving measurable pipeline growth through strategic planning, data governance, and team leadership. Collaborate with cross-functional...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$210K - $250K *

Lead the charge in therapeutic area strategy and scientific innovation, overseeing discovery portfolios across biologics and small molecules. Drive sustainable pipeline generation and align discovery...

1 week ago

  •   11 - 15 years exp.  •   Transportation

$80K - $95K *

Accelerate progress at a dynamic automotive SaaS company by owning the Mid-Market segment. Drive new business with multi-location auto repair groups, shaping strategies and building a scalable sales p...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$145K - $220K *

Join a team that's shaping the future of AI by leading enterprise sales for innovative AI solutions. Engage with top security and AI leaders to drive impactful evaluations and foster long-term partner...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in driving revenue growth and team performance by developing innovative sales strategies, coaching talent, and fostering client relationships to enhance business outcomes in technology...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$250K - $286K *

Shape the future of sales by leading a dynamic team to drive new business, refine strategies, and enhance customer experiences in a fast-paced SaaS environment, while mentoring leaders and achieving a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Discover your potential as you drive enterprise sales in the CPG sector, building relationships with iconic brands. Leverage insights and solutions to develop strategies that enhance client success an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$95K - $115K *

Join us in enhancing sales operations by providing critical analytics and incentive compensation support. Collaborate with cross-functional teams to drive insights, improve decision-making, and ensure...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.