Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.
Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.
Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.
Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.
Pediatric Focused Registered Nurse (RN) - Huntersville Emergency Department
$79K - $118K *
Transform patient care as a skilled RN in a dynamic emergency department, providing comprehensive treatment for diverse cases. Collaborate with a dedicated team to enhance patient outcomes in a fast-p...
1 week ago
Clinical Pharmacist - Levine Cancer - Oncology Infusion Pharmacy Morehead FT
$114K - $171K *
Join a team dedicated to optimizing pharmaceutical care by designing and overseeing medication therapy regimens. Leverage your expertise to support patient education and collaborate with healthcare pr...
3 weeks ago
Source to Pay (S2P) Workstream Lead
$110K - $130K *
Join a team that's driving the implementation of Oracle Cloud Source to Pay solutions. Leverage your expertise in business processes and technology to lead workshops, configure software, and support c...
1 week ago
$100K - $120K *
Drive profitable growth by leading strategic account planning and customer engagement. Collaborate with cross-functional teams to enhance customer satisfaction and identify new business opportunities...
3 weeks ago
$80K - $95K *
Lead the charge in optimizing plant operations, enhancing productivity, and maintaining equipment efficiency. Oversee logistics, employee training, and continuous improvement initiatives while ensurin...
Reposted 1 week ago
Site Contracts Specialist II or Sr. Site Contracts Specialist
$56K - $115K *
Join a dynamic team as a Site Contracts Specialist, where you will negotiate and manage clinical trial agreements. Lead contract discussions, mitigate risks, and collaborate with key stakeholders to e...
2 weeks ago
$80K - $95K *
Join a team that's dedicated to optimizing privacy management processes and compliance technology. This role supports platform administration, user engagement, and operational improvements, ensuring e...
2 days ago
Named Enterprise Account Executive- Mortgage
$125K - $150K *
Champion relationships with top mortgage lenders, driving business growth through consultative sales. Leverage Plaid's offerings to enhance loan origination and underwriting, while collaborating with...
4 days ago
$130K - $160K *
Lead the strategy and execution of paid search campaigns, optimizing performance and driving growth. Collaborate with cross-functional teams to enhance conversion rates and mentor team members in best...
1 week ago
$80K - $95K *
Deliver impactful telecom design solutions by overseeing projects, enhancing production efficiency, and collaborating with designers and project managers to meet quality standards and client expectati...
2 days ago
Community Partnership Manager (Account Executive)
$77K - $85K *
Strategize meaningful partnerships by engaging with community organizations. Drive initiatives in public health, leveraging relationship-building and sales skills to foster collaboration in the health...
Reposted 2 weeks ago
$150K - $180K *
Invent and evolve architectural strategies for cloud-native AI platforms at scale. Lead design, deployment, and infrastructure excellence, driving innovation while mentoring teams and shaping technica...
2 weeks ago
Business Title Registered Nurse Ambulatory & Outpatient
$73K - $110K *
Join a team that's dedicated to delivering exceptional patient care while utilizing your nursing expertise. Engage in quality initiatives, collaborate with diverse healthcare professionals, and promot...
3 weeks ago
Senior Manager, Release Engineering & Site Reliability (DevOps , CI/CD)
$196K - $292K *
Elevate the quality of software qualifications by leading a high-performing CI/CD engineering team. Drive automation and operational excellence, ensuring readiness for partner environments while colla...
3 weeks ago
Vice President, Enterprise Market Lead - Strategic Accounts
$175K - $210K *
Shape the future of healthcare technology by leading strategic accounts, driving revenue growth, and fostering executive relationships. Own the sales lifecycle, expand services, and influence cross-fu...
1 week ago
$100K - $120K *
Engage with diverse stakeholders to drive sales initiatives, source new clients, and expand existing accounts. Leverage strong prospecting and strategic relationship-building skills in a fast-paced, c...
1 week ago
Sales Representative New Business-Southeast
$80K - $100K *
Lead the charge in expanding our market presence through proactive sales initiatives and strategic growth plans, targeting distribution channels and developing key customer relationships to drive new...
Reposted 2 weeks ago
Software Engineer, Tech Lead - Supply Chain
$160K - $225K *
Lead the charge in enhancing inventory and supply chain systems through effective planning, optimization, and analytics. Drive technology choices while mentoring a team to ensure high-quality software...
Reposted 1 week ago
Senior Associate, Launch Manager, US
$90K - $110K *
Champion client success by managing onboarding projects, ensuring smooth implementation, maximizing value delivery, and fostering cross-functional collaboration to drive significant business impact an...
Reposted 1 week ago
$100K - $120K *
Drive excellence in licensing operations by leading a dedicated team, managing key client portfolios and ensuring high-quality application processes while fostering a culture of accountability and con...
Reposted 2 weeks ago
Life, Annuity & Group Benefits Operations Consultant - Sr. Manager
$124K - $280K *
Innovate client operations by leading impactful projects in life, annuity, and group benefits sectors. As a Senior Manager, drive excellence through strategic insights, team coaching, and optimized se...
2 weeks ago
Life, Annuity & Group Benefits Operations Consultant - Sr. Manager
$124K - $280K *
Lead the drive for operational excellence in the Insurance sector, utilizing strategic insights to enhance client service. Manage complex projects while coaching teams to innovate and achieve impactfu...
2 weeks ago
Senior Enterprise Account Executive
$125K - $150K *
Grow your career with a leading payroll solution provider, driving enterprise sales and developing client relationships in large organizations while managing complex sales cycles and achieving signifi...
Reposted 5 days ago
$158K - $326K *
Join a dynamic team to negotiate complex SaaS and cloud agreements, supporting strategic partnerships across multiple functions. Play a key role in driving Pinterest's cloud strategy and operationaliz...
1 week ago
Mid-Market Account Executive, New Business (API/CPaaS)
$85K - $112K *
Join a team that's driving innovation in communication technologies. Leverage your sales expertise to expand adoption of our APIs in the Mid-Market segment, collaborating across teams to deliver value...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.
Which North Carolina cities have professional job opportunities?
Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.
Does Ladders list jobs paying $100,000 or more?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.
How can I search for jobs in North Carolina?
Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.