Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$100K - $120K *

Shape the future of regional economic development by leading strategies, assessing site-readiness, and collaborating with public agencies to attract and retain businesses in vibrant communities...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$160K - $200K *

Shape the future of Strategic Sales by leading a dynamic team focused on high-value clientele. Drive growth, coach top talent, and foster a collaborative culture to achieve ambitious revenue targets i...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock your potential by shaping business strategy and workforce capabilities. Collaborate with leaders to drive organizational effectiveness, talent management, and transformation initiatives across...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$65K - $101K *

Explore the dynamic world of procurement as you evaluate vendor quotes, track purchasing actions, and ensure compliance in IT materials for a key Government program. Play a vital role in optimizing pr...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$145K - $175K *

Join our team to drive the technical direction of our Internal Developer Platform, enhancing workflows and tooling for engineering teams. You'll lead multi-quarter strategies, ensuring reliable delive...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$88K - $105K *

Lead revenue integrity initiatives by optimizing charge capture and compliance processes. Collaborate effectively with cross-functional teams to enhance performance and ensure audit readiness, driving...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Engage with local stakeholders to advance community development initiatives, ensuring alignment with data center goals. Collaborate with internal teams to optimize strategies and maintain relationship...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Champion the growth of your career as a lead Employment and Labor partner, leveraging your expertise in depositions, motions, and trial preparations to deliver strategic legal solutions and build clie...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$180K - $220K *

Elevate your legal career as you provide expert guidance in Employment and Labor law, handling depositions, drafting motions, and preparing cases for trial in a dynamic environment that emphasizes str...

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$108K - $130K *

Champion strategic sourcing initiatives across diverse categories, leading a high-performing team to drive measurable value. Foster partnerships, negotiate with suppliers, and implement innovative sol...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$105K - $127K *

Engage with healthcare providers to drive enterprise sales, leveraging strategic relationships and operational rigor. Shape go-to-market strategies while collaborating cross-functionally to enhance cl...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Develop innovative measurement solutions by leveraging data science expertise to solve complex marketing challenges. Collaborate closely with customers and cross-functional teams to deliver insights...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $180K *

Lead the charge in enhancing procurement processes through collaboration, analytics, and strategic initiatives. Engage directly with clients to drive efficiency and value in supply chain management wh...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$188K - $282K *

Lead the enterprise talent management strategy, driving talent assessment, development, and succession planning while partnering with senior leaders to enhance organizational agility and performance m...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Empower your career by leading strategic application initiatives, collaborating with cross-functional teams to enhance investment solutions, and driving continuous improvement across the application l...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$212K - $249K *

Lead the charge in transforming customer support with AI-driven strategies, managing cross-functional programs, and executing complex initiatives to enhance customer experience and operational efficie...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Transform existing accounts by identifying growth opportunities, building executive relationships, and developing strategic engagement plans to drive revenue and maintain strong client partnerships fo...

US-AnywhereRemote

1 month ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Lead the charge in managing a large-scale FHWA communications program, ensuring effective contract leadership, quality management, and stakeholder engagement across a multidisciplinary team to deliver...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$120K - $130K *

Accelerate progress at driving revenue growth through strategic partnership development. Build and maintain strong relationships with senior executives while leading complex sales negotiations and pro...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead the charge in strategic sourcing initiatives, overseeing procurement of academic software and services while managing a dynamic team to enhance supplier relationships and drive value across the u...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $105K *

Join a supportive team and provide exceptional therapy services to children and adults. Engage in a fulfilling, clinic-based role focused on enhancing the well-being of patients, with flexibility for...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of enterprise advertising by driving growth across a strategic portfolio. Engage with executive clients, reactivation of dormant accounts, and foster collaboration, leveraging your ex...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Join a team that's transforming customer relationships by driving growth, fostering strong partnerships, and delivering tailored solutions. Be a key contributor in maximizing retention and exploring n...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Innovate your career by leading SAP S/4HANA transformations, guiding clients through Order to Cash solutions, and enhancing operational efficiency while establishing strong partnerships and delivering...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.