Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$135K - $169K *
Unlock your potential by leading complex design initiatives that define product strategy and influence cross-functional teams. Drive innovation in UX and create impactful solutions while shaping the f...
Reposted 3 weeks ago
Senior Organic Growth Strategist
$100K - $120K *
Lead organic growth strategies for high-value accounts, driving retention and expansion with minimal oversight. Mentor junior strategists, set measurement standards, and support sales efforts while en...
2 weeks ago
$97K - $133K *
Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...
5 days ago
Senior Director of Communications (United States)
$200K - $220K *
Unlock potential by leading the communications strategy across external, internal, and crisis communications. Serve as a trusted advisor to executives, developing narratives and building media relatio...
4 weeks ago
$182K - $198K *
Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...
1 week ago
$130K - $145K *
Transform the global recruitment function by leading a small team, optimizing processes, and leveraging AI to enhance efficiency and candidate experience while personally closing roles and driving per...
Yesterday
Senior Director, Product, Security and Privacy
$260K - $300K *
Transform product development by ensuring compliance with laws and regulations. Collaborate with cross-functional teams to proactively manage legal risks throughout the product lifecycle, empowering r...
4 weeks ago
$160K - $170K *
Innovate integrated marketing strategies to drive demand and engagement. Lead cross-channel campaigns tailored to a defined audience, measuring success with clear metrics while collaborating with vari...
Reposted 1 month ago
$92K - $115K *
Unlock potential by leading requirements documentation for software projects. Collaborate with stakeholders and technical teams to ensure successful delivery throughout the project lifecycle, while su...
5 days ago
$175K - $210K *
Unlock potential by driving sales and business development for RWD solutions in the life sciences sector. Build relationships with senior stakeholders and leverage market insights to enhance client en...
2 weeks ago
$120K - $150K *
Transform enterprise strategies by leading discovery and building account plans that align marketing goals with AI investments, driving growth and success for senior marketing leaders...
2 weeks ago
$100K *
Drive data-driven decision-making by developing automated reporting solutions. Collaborate with cross-functional teams to enhance enterprise reporting, ensuring accuracy and efficiency while translati...
2 weeks ago
$100K - $110K *
Take ownership of the month-end close and general ledger, building a robust accounting foundation for a high-growth company. Collaborate with cross-functional teams to ensure accurate financial report...
3 weeks ago
Strategic Account Executive, SaaS Sales
$90K - $115K *
Transform the sales landscape by owning the full cycle for SaaS solutions, building relationships with key stakeholders in K-12 districts, and driving impactful technology adoption to enhance student...
1 week ago
$133K - $180K *
Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...
1 month ago
Business Development Manager, Enterprise
$135K - $146K *
Innovate strategic partnerships and drive revenue growth in NTN and IoT sectors. Cultivate relationships with global carriers, negotiate agreements, and identify new business opportunities to establis...
4 days ago
Executive Producer - Mainstream, Narrative & New Experiences (Games)
$350K - $500K+*
Lead and innovate in game production, driving strategic initiatives and excellence across a diverse portfolio. Collaborate with teams to deliver high-quality gaming experiences while fostering a cultu...
2 weeks ago
$191K - $305K *
Champion innovative healthcare solutions by leveraging clinical expertise to enhance value-based strategies, drive operational excellence, and foster strategic partnerships for improved member care an...
2 weeks ago
$110K - $150K *
Drive strategic growth by building partnerships in the oncology sector. Engage with physician practices, support contract negotiations, and enhance service delivery through effective collaboration and...
Reposted 1 month ago
$70K - $100K *
Join a team that's dedicated to enhancing financial operations through meticulous month-end close processes, reconciliations, and compliance. Collaborate cross-functionally to drive efficiency and acc...
1 week ago
$119K - $186K *
Execute strategic legal counsel and project management for technology agreements, focusing on healthcare solutions. Collaborate with teams to navigate complex regulatory issues and negotiate high-volu...
4 days ago
Senior Technical Account Manager
$125K - $150K *
Lead the charge in technical account management by enhancing integrations, ensuring operational stability, and facilitating product adoption with financial partners. Drive impactful projects that shap...
Reposted 1 month ago
Product Development Senior Analyst
$72K - $99K *
Join a team that's dedicated to innovating insurance products, driving growth, and ensuring regulatory compliance. Collaborate with key stakeholders throughout the product lifecycle while contributing...
Reposted 1 month ago
Senior Financial Analyst, Treasury
$99K - $132K *
Advance your career as a Senior Financial Analyst in Treasury, focusing on cash management, corporate finance, and cross-functional collaboration. Drive impactful financial strategies while enhancing...
4 days ago
$131K - $182K *
Empower revenue teams by leading a dynamic group of Revenue Enablement Managers. Drive ongoing performance through strategic coaching, hands-on training, and AI-first initiatives, ensuring alignment a...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.